The National Institute of General Medical Sciences (NIGMS) awarded a $232,414 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Texas State University, a Hispanic-Serving Institution, to acquire a continuous-wave X-band electron paramagnetic resonance (EPR) spectrometer. This instrument will enable the university to conduct sensitive, variable-temperature measurements of paramagnetic biological and synthetic species, supporting their research on...
This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) provides $1,899,160 to Northwestern University to acquire a state-of-the-art pulsed Q-band electron paramagnetic resonance (EPR) spectrometer. The instrument will be a multi-user shared resource at the university's Integrated Molecular Structure Education and Research Center (IMSERC) facility, accessible to all Northwestern researchers...
This Project Grant award from the National Science Foundation's Biological Sciences (CFDA 47.074) program provides $743,852 to Saint Louis University (SLU) to acquire an XTALAB SYNERGY-R single crystal diffractometer. This state-of-the-art scientific instrument will enable researchers across 13 different SLU colleges, as well as collaborators from Southern Illinois University Edwardsville, to collect high-quality X-ray diffraction data from organic compounds and biological macromolecules. The...
This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) provides $416,625 to Saint Louis University to develop innovative optical tools to control endogenous G protein-coupled receptors (GPCRs) and G proteins at exclusive subcellular locations. The award aims to advance the understanding of GPCR signaling regulation in health and disease, including potential applications in...
The National Institute of General Medical Sciences (NIGMS) awarded a $1,979,999 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to The New York Structural Biology Center, Inc. (NYSBC). The funding will be used to acquire a Bruker BioSpin Fast Shuttle System (FSS) apparatus to be installed on an existing 700 MHz NMR spectrometer at NYSBC. The FSS apparatus is a technological breakthrough that enables measurements of spin-lattice relaxation rate constants in...
The National Institute of General Medical Sciences (NIGMS) awarded a $599,733 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Florida State University (FSU). The grant supports the development of a new technology pathway towards 1.5 GHz 1H NMR spectroscopy by building a 28.2 T (1.2 GHz 1H)/1PPM, all-superconducting NMR demonstrator magnet. The project will utilize high-temperature superconductors (HTS) Bi-2212 and Bi-2223 nested inside an existing 12...
The New York Structural Biology Center, Inc. has been awarded a $1,995,724 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) to acquire a state-of-the-art 800 MHz NMR spectrometer console and associated probes. This instrumentation will enhance the capacity of the existing 800 MHz NMR system to support a range of NIH-funded structural biology research, from fundamental studies of biomolecular...
This Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) provides $750,000 to the University of Illinois to acquire a Bruker Avance NEO Nuclear Magnetic Resonance (NMR) spectrometer system. The NMR system, which operates at 500 MHz and includes an automated sample changer and cryogenically-cooled probe, will be used to support the research programs of the university's synthetic organic, inorganic, physical, and chemical...
The National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training Program (CFDA 93.859), awarded a $1,469,739 Project Grant to the Research Foundation of the City University of New York (RFCUNY) to purchase a TIMSTOF-FLEX MALDI-2 high-resolution mass spectrometer. This advanced instrumentation will support biomedical research projects across 12 laboratories from CUNY and nearby institutions, focusing on areas such as conformational dynamics of...
This $151,080 Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) will be used to acquire a circular dichroism (CD) spectropolarimeter instrument by the University of Massachusetts Dartmouth. The instrument will enhance the university's biomedical research and education capabilities in areas such as investigating the structures of chiral nanoparticles and biomolecules. This specialized equipment...
The National Institute of General Medical Sciences (NIGMS) awarded a $1,600,000 Project Grant under the Biomedical Research and Research Training (CFDA 93.859) program to Saint Louis University. The grant will fund the purchase of a high-sensitivity Bruker Q-band ELEXSYS E580 Pulse EPR Spectrometer to enable structural dynamics studies of proteins and their complexes, as well as the training of students and researchers. The instrument will support basic research projects from NIH-funded investigators at Saint Louis University and Washington University in St. Louis, spanning topics such as membrane transporters, protein secretion, blood clotting, DNA repair, immunothrombosis, protein translation, antimicrobial peptide transport, ion channels, and membrane protein oligomerization. The award period is from Sep 1, 2024 to Aug 31, 2025.