This Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $249,951 to the University of Puerto Rico (UPR) Rio Piedras Campus to purchase an X-band continuous-wave electron paramagnetic resonance (EPR) spectrometer. This state-of-the-art EPR instrument will enhance the interdisciplinary and multi-campus biomedical research capabilities of UPR's College of Natural Sciences and...
The National Institute of General Medical Sciences (NIGMS) awarded a $3,346,528 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Saint Louis University. The grant will fund the acquisition of a high-sensitivity Bruker Q-band ELEXSYS E580 Pulse EPR Spectrometer, a critical instrument enabling structural dynamics studies of proteins and their complexes, as well as training for students and researchers. The instrument will support a range of NIH-funded...
The National Science Foundation (NSF), through its Integrative Activities program (CFDA 47.083), awarded a $1,815,774 project grant to Florida State University (FSU) to acquire a state-of-the-art pulsed electron paramagnetic resonance (EPR) spectrometer operating at 9 and 34 gigahertz frequencies. This advanced instrument will enable research and education in a wide range of fields, including chemistry, biochemistry, physics, materials science, and quantum information science. The spectrometer...
This Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) provides $194,590 to Texas State University to acquire a ZEISS AXIO OBSERVER 7 wide-field fluorescence microscope with APOTOME-3 and live-cell imaging capabilities. The microscope will be housed in the university's Shared Resource Operations and will directly strengthen the research programs of three NIH-supported investigators in the Department...
The National Science Foundation awarded the University of Louisville a $199,999 Project Grant under the Mathematical and Physical Sciences federal grant program (CFDA 47.049) to acquire an upgraded variable temperature electron paramagnetic resonance spectrometer. The spectrometer will support research by Professor Craig Graperhaus and colleague Xiang Zhang in areas such as chemistry, physical chemistry, biology, and biochemistry. It will enable investigations of electrocatalysts,...
This federal Project Grant award of $147,656 from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) will support advanced spectroscopic characterization of enzymatic intermediates containing iron-sulfur (Fe-S) clusters. The research will utilize electron paramagnetic resonance (EPR) and parahydrogen-induced polarization (PHIP) nuclear magnetic resonance (NMR) techniques, along with isotopic labeling, to study the mechanisms...
The National Institute of General Medical Sciences (NIGMS) awarded a $599,733 Project Grant under the Biomedical Research and Research Training Program (CFDA 93.859) to Florida State University (FSU) to develop a new technology pathway towards 1.5 GHz 1H NMR magnets. The project aims to build a 28.2 T (1.2 GHz 1H)/1PPM, all-superconducting NMR demonstrator magnet using high-temperature superconductors (HTS) Bi-2212 and Bi-2223, nested inside an existing 12 T low-temperature superconductor...
This $151,080 Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) will provide a Circular Dichroism (CD) Spectropolarimeter instrument to the University of Massachusetts Dartmouth. The instrument will enhance the university's biomedical research and educational capabilities in southern Massachusetts, supporting ongoing investigations into the structures of chiral nanoparticles and biomolecules. The CD...
The National Institute of General Medical Sciences (NIGMS) awarded a $344,400 Project Grant (CFDA 93.859 Biomedical Research and Research Training) to The University of Texas Southwestern Medical Center to develop new tools and approaches to enhance cryo-electron microscopy (cryo-EM) and cryo-electron tomography (cryo-ET) imaging techniques. The objectives are to (1) reduce electron-induced radiolysis of frozen-hydrated biological specimens to improve the resolution of cryo-EM/ET images and/or...
This Project Grant award from the National Institutes of Health (CFDA 93.351 - Research Infrastructure Programs) provides $425,000 to The Johns Hopkins University to acquire a 500 MHz NMR spectrometer to support small-molecule chemistry research at the Johns Hopkins School of Medicine. The new state-of-the-art NMR system will replace an older, frequently malfunctioning 500 MHz Bruker instrument and serve a large user base of NIH-funded researchers across multiple clinical and basic science...