This Project Grant from the National Institutes of Health's National Institute of Neurological Disorders and Stroke will fund the development of advanced tools for genetically targeted all-optical electrophysiology in behaving mice. Specifically, the $4,381,836 award to President and Fellows of Harvard College, doing business as Harvard University, will support efforts to co-develop two-photon excitable genetically encoded voltage indicators and a new type of two-photon voltage-imaging...
The National Institutes of Health National Institute of Neurological Disorders and Stroke awarded $3.6 million under the 21st Century Cures Act Brain Research through Advancing Innovative Neurotechnologies program (CFDA 93.372) to Stanford University. The project grant will support development of a noninvasive, dynamically programmable in vivo light source for rapid brain-wide optogenetic screening. Specifically, the awardee aims to develop mechanoluminescent nanoparticles with distinct emission...
This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), will provide $2,565,783 to Oregon Health & Science University (OHSU) from September 1, 2023 to August 31, 2026 to develop novel genetically encoded sensors and actuators for monitoring and manipulating neuromodulatory signaling activities in the brain at the cellular and circuit levels. The project aims to enable large-scale in vivo...
The National Institutes of Health National Institute of Neurological Disorders and Stroke awarded $1,852,675 under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies program (CFDA 93.372) to the University of California, Los Angeles from August 1, 2022 to July 31, 2025. The award will support the development of light field tomographic microscopy for kilohertz volumetric imaging of neuronal action potentials in awake behaving mice. Specifically, the...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Trustees of Columbia University in the City of New York, doing business as the Health Sciences Division, a $2,554,313 federal Project Grant under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372). The grant, which runs from Sep 1, 2023 to Aug 31, 2026, will support research to determine if targeted in vivo manipulations of local circuit control...
The National Institute of Neurological Disorders and Stroke (NINDS), a component of the National Institutes of Health (NIH), awarded a $597,844 Project Grant under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative program (CFDA 93.372) to The Regents of the University of California, San Francisco (UCSF). This 3-year project, effective September 1, 2024, aims to map the functional G-protein coupled receptor (GPCR) landscape in neurons...
This federal Cooperative Agreement award from the National Institute of Neurological Disorders and Stroke (NINDS), under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372), is providing $361,992 to The Regents of the University of California, Berkeley (UC Berkeley) over a 4-year period from September 1, 2024 to August 31, 2028. The primary goals of this project are to further optimize UC Berkeley's Free-space...
This federal Project Grant award of $354,600.00 from the National Institute of Neurological Disorders and Stroke (NINDS), under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372), will support the development of novel methodologies for simultaneous, distributed perturbation of multiple cortical regions using patterned light in head-fixed mice. The goal is to infer how large-scale patterns of cortical activity underlie...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, aims to develop novel nano- and immuno-probes for multicolor electron microscopy of neural cells and tissues. The $621,500.00 award to President and Fellows of Harvard College will fund research to establish two new methods for multicolor electron microscopy: one using...
The Johns Hopkins University was awarded a $2,008,605 Project Grant under the National Institute of Neurological Disorders and Stroke's 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372). The grant funding will support the development of an "Autonomous Rapidly Adaptive Multiphoton Microscope for Neural Recording and Stimulation." This adaptive multiphoton microscope system will leverage hybrid volumetric scanning,...