Project Grant RF1NS133976

Award Date 9/20/23
Completion Date 8/31/26
Dollars Obligated $2M
Federal Grant Program
93.372
Assistance Type
Project Grant
Place of Performance
Maryland, USA
Similar Awards
The University of Minnesota was awarded a $3,972,414 Project Grant from the National Institute of Neurological Disorders and Stroke within the Department of Health and Human Services to develop an electro-optical multiphoton microscope. The microscope will leverage advances in electro-optical beam deflection to enable random-access multiphoton interrogation of neurons and synapses with sub-microsecond access times. This will allow neuroscientists to collect the simultaneous recordings needed...
The Johns Hopkins University received a $1,490,248 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372). The award supports a 3-year research project titled "Cortical Circuit Dynamics Underlying Multisensory Decision Making." The project aims to investigate how the brain integrates visual, vestibular, and kinesthetic...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Trustees of Columbia University in the City of New York, doing business as the Health Sciences Division, a $2,554,313 federal Project Grant under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372). The grant, which runs from Sep 1, 2023 to Aug 31, 2026, will support research to determine if targeted in vivo manipulations of local circuit control...
The National Institutes of Health National Institute of Neurological Disorders and Stroke awarded $1,852,675 under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies program (CFDA 93.372) to the University of California, Los Angeles from August 1, 2022 to July 31, 2025. The award will support the development of light field tomographic microscopy for kilohertz volumetric imaging of neuronal action potentials in awake behaving mice. Specifically, the...
The National Eye Institute (NEI) awarded a $237,914 Project Grant (CFDA 93.867 Vision Research) to The Johns Hopkins University to develop a novel technology for high-density mapping of neuronal activity in non-linear brain structures and circuits. The project aims to design ultra-flexible neural probes that can be conformally deployed along curved brain regions, in contrast to conventional linear implantation methods. This novel approach seeks to significantly improve the spatial resolution...
This National Science Foundation (NSF) Computer and Information Science and Engineering (CFDA 47.070) Project Grant award of $329,099 to The Johns Hopkins University supports research to uncover the functional architecture of the brain and understand how different neural systems coordinate to enable flexible, robust intelligence. The project aims to develop new computational models to analyze brain activity data and identify the subsystems underlying key behaviors like navigation and...
The National Institutes of Health National Institute of Neurological Disorders and Stroke awarded $3.6 million under the 21st Century Cures Act Brain Research through Advancing Innovative Neurotechnologies program (CFDA 93.372) to Stanford University. The project grant will support development of a noninvasive, dynamically programmable in vivo light source for rapid brain-wide optogenetic screening. Specifically, the awardee aims to develop mechanoluminescent nanoparticles with distinct emission...
The U.S. National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $1,705,580 Cooperative Agreement under the "Discovery and Applied Research for Technological Innovations to Improve Human Health" (CFDA 93.286) program to The Johns Hopkins University. This grant supports the development of a "BRAIN CONNECTS: A SCALABLE AUTOMATED PROOFREADING FRAMEWORK FOR CONNECTOMICS" project, which aims to advance automated techniques for analyzing complex brain...
The University of Chicago received a $3.89 million Project Grant from the National Institutes of Health National Institute of Neurological Disorders and Stroke under the 21st Century Cures Act Brain Research through Advancing Innovative Neurotechnologies program. The grant will fund research from August 2022 through August 2025 to directly measure and manipulate the spiking activity of locus coeruleus and ventral tegmental area axons in the hippocampus of mice during hippocampal-dependent...
The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $187,831 Project Grant under the "Discovery and Applied Research for Technological Innovations to Improve Human Health" (CFDA 93.286) program to the University of California, Davis. The grant will fund the development of a miniature, two-photon microscope capable of simultaneously imaging and manipulating neural activity in freely behaving mice. Key deliverables include a compact fiber-optic scanner,...

The Johns Hopkins University was awarded a $2,008,605 Project Grant under the National Institute of Neurological Disorders and Stroke's 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372). The grant funding will support the development of an "Autonomous Rapidly Adaptive Multiphoton Microscope for Neural Recording and Stimulation." This adaptive multiphoton microscope system will leverage hybrid volumetric scanning, parallel coded excitation, and machine learning algorithms to autonomously optimize neural activity recordings. The goal is to maximize the number and signal-to-noise ratio of recorded neurons in response to their motion and activity, which will enable improved mapping of functional neural circuits. The 3-year project (9/20/2023 - 8/31/2026) will involve constructing the microscope system, developing adaptive hardware/software solutions, and benchmarking the system's performance in brain slice and in vivo studies of the auditory cortex.

Generated 7/16/24, 3:11 AM