The National Institute of Mental Health (NIMH), under the CFDA 93.242 Mental Health Research Grants program, awarded a $3,231,590 Project Grant to Weill Medical College of Cornell University. The award, effective September 1, 2023, aims to leverage longitudinal survey and electronic health record data to examine the long-term impact of the COVID-19 pandemic on child mental health, including new or worsening conditions and suicidal ideation/attempts. The study will quantify these outcomes,...
The National Institute of Mental Health (NIMH) awarded a $3,325,812 Cooperative Agreement under the Mental Health Research Grants (CFDA 93.242) program to Yale University. The 5-year project, titled "Coordinating Individually Measured Phenotypes to Advance Mental Health Research" (IMPACT-MH), aims to advance computational approaches for generating precise clinical phenotypes to improve mental health research and patient care. Key elements of the project include: Establishing a data...
This Project Grant award from the National Institute of Mental Health (NIMH) under CFDA program 93.242 - Mental Health Research Grants provides $797,157 to Yale University to conduct research on understanding brain circuit dysfunction in individuals with neuropsychiatric manifestations of post-acute sequelae of SARS-CoV-2 infection (Neuro-PASC). The 5-year project aims to leverage Yale's expertise in neuroscience and neuroimaging, as well as established Neuro-PASC patient cohorts, to identify...
This federal Project Grant award from the National Institutes of Health National Institute of Mental Health provides $6,499,884 to Yale University under the Mental Health Research Grants program (CFDA 93.242) to study the longitudinal nervous system consequences of SARS-CoV-2 in people with HIV-1 treated in early infection. The award will fund research from September 2022 to September 2025 to analyze pre- and post-COVID-19 data from a cohort of early antiretroviral therapy-treated people with...
The National Institute of Mental Health (NIMH) awarded a $4,159,108 Cooperative Agreement under the Mental Health Research Grants program (CFDA 93.242) to Yale University to conduct the IMPACT-MH project. The project aims to collect longitudinal data over 2 years from a large sample of 2,400 individuals highly enriched for psychopathology across a wide range of traditional diagnoses. The goal is to identify predictive markers of symptom change using a variety of assessments, including electronic...
This Project Grant award from the National Institute of Mental Health (NIMH) under CFDA 93.242 - Mental Health Research Grants provides $1,932,991 to conduct research on the neural computations underlying learning, decision-making, and memory. The goal is to characterize core computations of value, uncertainty, and prediction error across cognitive processes and domains, and to identify associations between these computations and symptoms of anxiety and stress-related disorders. The research...
The National Institute of Mental Health (NIMH) awarded a $833,123 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to Cedars-Sinai Medical Center in West Hollywood, CA. The project, titled "SARS-COV-2 AND SOCIAL DETERMINANTS OF HEALTH IMPACT ON INFLAMMATION ASSOCIATED DEPRESSION RISK (SSIDR)," aims to provide a comprehensive understanding of how SARS-CoV-2 infection and social determinants of health moderate the development of depression through changes in...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $1,995,095 to Yale University to conduct research on expanding the genetic understanding of major depressive disorder (MDD) and anxiety disorders (ANX). The 5-year project aims to leverage the large, diverse Veteran Affairs Million Veteran Program (MVP) dataset to identify genetic risk loci for MDD, ANX, and related traits, investigate medication...
This federal Project Grant award of $3,155,102 from the National Institute of Mental Health (CFDA 93.242 - Mental Health Research Grants) aims to assemble a large global consortium to evaluate the social determinants of mental health outcomes related to the COVID-19 pandemic. The project, titled "International Evaluation of Modifiable Social Determinants of Health on COVID-Related Mental Health Outcomes," will integrate longitudinal data from 23 international cohorts comprising...
The National Institute of Mental Health (NIMH) awarded a $183,096 Project Grant with the CFDA program title "Mental Health Research Grants" (93.242) to the University of Maryland, Baltimore. The grant will fund a 3-year research project to investigate the structural, functional, and neurobehavioral consequences of SARS-CoV-2 infection in adolescents. The project aims to identify changes in brain morphometry, microstructure, and function associated with prior COVID-19 infection, and...
The National Institutes of Health National Institute of Mental Health awarded Yale University $7,389,444 under the Mental Health Research Grants program (CFDA 93.242) on September 1, 2022 for a project concluding on August 31, 2025.
The award will support Yale University in conducting a multivariate investigation to identify latent factors linking internalizing disorders such as anxiety, major depressive disorder, and posttraumatic stress disorder with COVID-19 outcomes including infection, hospitalization, and critical illness. The university will investigate regulatory mechanisms of these latent factors across multiple omics domains, tissues, and cell types in parallel with testing interactions between internalizing disorders and blood-based transcriptomic and epigenomic changes associated with COVID-19 morbidity and psychological stress. Findings will provide a multi-dimensional perspective on processes underlying associations between COVID-19 outcomes and internalizing disorders.