Project Grant RF1DA056397
- Federal Project Grant Award Summary New York University has been awarded $201,250 by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) for a two-year project period from June 1, 2025, through May 31, 2027. This Project Grant supports basic neuroscience research investigating the synaptic organization of cholinergic interneurons in the nucleus accumbens, a brain region critical to motivated behaviors and implicated in substance use...
- This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $1,080,885 to the University of Southern California (USC) from September 2024 to September 2027. The funding supports the development of novel neural network models that can capture the nonlinear dynamics of large-scale brain networks and their relationship to behavior. The models will have flexible inference capabilities, enabling real-time,...
- Federal Grant Award Summary New York University received a $390,687 Project Grant award from the National Institute on Drug Abuse under the Drug Use and Addiction Research Programs (CFDA 93.279) beginning August 1, 2025 and concluding April 30, 2030. The award supports basic neuroscience research investigating multiregional brain computations underlying value-based decision-making and belief updating. The research characterizes how the orbitofrontal cortex (OFC) interacts with the dorsal...
- This two-year, $140,108 project grant from the National Institutes of Health's National Institute of Neurological Disorders and Stroke will fund research into the co-regulation of striatal dopamine and acetylcholine in associative reward learning. The grantee, The Trustees of Columbia University in the City of New York, will investigate how these two neuromodulators interact to drive associative reward learning processes. Specifically, the researchers will test the hypothesis that striatal...
- Federal Project Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded a $811,112 Project Grant to the Regents of the University of California, San Francisco effective July 1, 2025 through March 31, 2030 under the Drug Use and Addiction Research Programs (CFDA 93.279). This neuroscience research project investigates the network and circuit dynamics supporting dopaminergic control of sudden insight learning in cue-reward associations. The research combines advanced neuroimaging...
- The University of Washington was awarded a $149,284 Project Grant by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) to investigate the role of specific subpopulations of prefrontal cortex pyramidal neurons in regulating drug-seeking behavior. The research aims to elucidate the factors that predispose individuals to addiction and confer vulnerability to relapse, with the goal of advancing understanding of the functional roles of...
- This Project Grant award of $1.35M from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) supports basic neuroscience research conducted by the University of Alabama at Birmingham from April 2025 through February 2030. The project investigates the mechanisms by which somatostatin-expressing interneurons (SST-INs) in the prelimbic region of the prefrontal cortex regulate reward-seeking behaviors, with particular emphasis on...
- This federal Project Grant award of $180,606.00 from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) will fund research at the Icahn School of Medicine at Mount Sinai to investigate the interplay between drug-induced long-term synaptic proteomic adaptations and the underlying transcriptional responses that drive these adaptations in a cell-type and circuit-specific manner within the brain's reward regions. The research aims to...
- This three-year, $4.93 million project grant from the National Institute on Drug Abuse will fund research into odor trail tracking behavior in mice. The grant supports three principal investigators at Harvard University who will study the algorithms and neural circuits underlying active sensation and continuous decision-making during this olfactory navigation behavior. The researchers will use behavioral, physiological, molecular and computational methods across three aims. In Aim 1, they will...
- This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), will fund research to elucidate the function of the ventral tegmental area (VTA) circuits in motivated behavior. The $629,844 award to Duke University will use bidirectional optogenetics, in vivo electrophysiology, photometry, and quantitative behavioral measures to investigate the roles of VTA dopamine and GABA neurons in learning and performance of...
This three-year, $2.31 million Project Grant from the National Institute on Drug Abuse will support research modeling the development of orientation selectivity, maps, and associated recurrent circuitry in primary visual cortex. Funded under the Drug Abuse and Addiction Research Programs (CFDA 93.279), the awardee, The Trustees of Columbia University in the City of New York, will build on prior discoveries to comprehensively account for mechanisms leading to orientation selectivity, maps, and nonlinear response properties in visual cortex without visual experience. Researchers will model how observed spontaneous input activity statistics instruct development, competition between on- and off-center inputs forming simple cells, co-development of feedforward and recurrent connections shaping response properties, and other phenomena. Outcomes aim to further understanding of circuit development yielding key visual processing functions and inform addiction research.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.2m | 9/7/22 | ||
| Not listed | $1.2m | 9/7/22 |