Project Grant RF1AG100511
- Federal Grant Award Summary The University of Kansas Medical Center Research Institute, Inc. received a $589,614 Project Grant award from the National Institute on Aging under the Aging Research program (CFDA 93.866), effective February 1, 2026, through December 31, 2030. The award funds the Cognitive Monitoring During Treatment for Alzheimer Disease (COMTAD) study, which will develop and validate a cognitive safety monitoring system designed to detect adverse side effects of anti-amyloid...
- Federal Grant Award Summary The University of Kansas Medical Center Research Institute, Inc. (KUMCRI) received a $1.11 million Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), awarded September 15, 2025, with completion targeted for May 31, 2030. The grant funds research investigating mitochondrial-nuclear communication mechanisms in Alzheimer's disease (AD), specifically examining how mitochondrial dysfunction leads to elevated lactate...
- Federal Project Grant Award Summary The National Institute on Aging awarded the University of Alabama at Birmingham a $5.06 million Project Grant (CFDA 93.866 – Aging Research) on September 15, 2025, for a four-year research initiative examining the impact of undiagnosed Alzheimer's disease and related dementias (ADRD) on healthcare utilization across geographic regions. The research project will integrate Medicare claims data with cognitive assessment data from the Reasons for Geographic and...
- Federal Grant Award Summary Braincheck, Inc. received a $497,782 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), awarded September 20, 2025, with completion targeted for September 19, 2026. The company is developing BrainCheck eConsult, a secure digital platform designed to facilitate asynchronous consultations between primary care providers (PCPs) and dementia specialists. This solution addresses a critical gap in dementia care access,...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded $3.23 million to the University of Kansas Center for Research Inc. under the Aging Research program (CFDA 93.866) to investigate the interplay between neuronal activity, synaptic dysfunction, and mitochondrial dysfunction in Alzheimer's disease. The project, initiated September 30, 2025, and running through August 31, 2029, will utilize mouse models of Alzheimer's disease to examine age-dependent and region-specific...
- Federal Grant Award Summary The University of Kansas Medical Center Research Institute, Inc. received a $155,504 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), awarded March 1, 2026, with completion targeted for September 7, 2027. The grant funds research investigating the associations between body composition, moderate-to-vigorous physical activity (MVPA), and cognitive function in adults with Down syndrome (DS). Given that individuals...
- Federal Project Grant Award Summary Kaiser Foundation Hospitals (Kaiser Permanente) received a $2,495,163 Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866) beginning September 15, 2025, with completion targeted for June 30, 2030. This R01 research project, "Missed Home Health Care in Older Adults with Dementia: Identifying Drivers, Outcomes, and Costs," delivers a comprehensive mixed-methods research initiative designed to identify key...
- Federal Grant Award Summary Brigham & Women's Hospital received a $3.69 million Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866) awarded on September 15, 2025, with a completion date of September 14, 2029. The award funds development of specialized large language models (LLMs) designed to extract Alzheimer's disease and related dementias (ADRD)-relevant clinical phenotypes from electronic health records (EHRs). The project addresses a critical...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded Indiana University Indianapolis $607,706 under the Aging Research program (CFDA 93.866) for a five-year project spanning March 1, 2026 through January 31, 2031. The project investigates short-term practice effects (STPE) in individuals with subjective cognitive decline (SCD)—self-reported cognitive changes without objective impairment that may signal early-stage Alzheimer's disease. The research aims to establish whether...
- Federal Project Grant Award Summary The National Institute on Aging (NIA), under the Aging Research program (CFDA 93.866), awarded a $129,876 Project Grant to The Washington University in St. Louis, Missouri, effective June 15, 2026, through March 31, 2031. This award supports research investigating the relationship between tau accumulation, white matter degeneration, and cognitive decline in preclinical Alzheimer disease (AD). The research leverages the Dominantly Inherited Alzheimer Network...
The University of Kansas Medical Center Research Institute, Inc. received a $3.25 million Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866), awarded July 1, 2026, with completion targeted for June 30, 2030. This grant funds the implementation and rigorous evaluation of the Brain Health Care Accelerator (BHCA), a comprehensive clinical and systems intervention designed to transform dementia care delivery in primary care settings. The BHCA integrates structured cognitive assessments, blood biomarkers (including plasma phosphorylated tau-217), electronic health record-embedded clinical decision support tools, and multidisciplinary specialty co-management clinics, complemented by primary care provider (PCP) training, clinical champion support, and workflow optimization incentives. The project will conduct a pragmatic stepped-wedge trial evaluation across 15 diverse primary care clinics within the University of Kansas Health System, engaging approximately 120 PCPs. Using the RE-AIM framework (Reach, Effectiveness, Adoption, Implementation, Maintenance), the grant deliverables include comprehensive evaluation of BHCA's clinical effectiveness in increasing Alzheimer's disease and related dementias (ADRD) diagnosis rates while shifting identification toward earlier cognitive stages, assessment of PCP adoption and implementation outcomes, and evaluation of diagnostic accuracy and appropriate biomarker usage to ensure high-quality diagnoses in primary care settings.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $3.3m | 6/19/26 |