Project Grant RF1AG090405
- This $2,497,615 federal Project Grant award, funded by the National Institute on Aging under the Aging Research program (CFDA 93.866), aims to evaluate the impact of new Medicare home health agency (HHA) payment policies on healthcare utilization and outcomes for Medicare beneficiaries with Alzheimer's disease and related dementias (ADRD). The project has three key objectives: 1) characterizing changes in the ADRD beneficiary population eligible for HHA services, 2) evaluating the effect of...
- This $322,286 federal Project Grant award from the National Institute on Aging's Aging Research program (CFDA 93.866) supports research to advance health equity in the use of novel treatments for Alzheimer's disease and related dementias (ADRD). The primary objectives are to: Conduct focus groups with diverse individuals affected by ADRD to understand their medication decision-making processes. Design and administer discrete choice experiments to learn how different treatment attributes are...
- The National Institute on Aging (NIA), under the Aging Research Federal Grant Program (CFDA 93.866), awarded a $129,330 Project Grant to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to conduct research on profiling and forecasting individual progression in Alzheimer's disease and related dementias (ADRD). The key objectives of this 5-year project are to: 1) deploy a multi-modal information framework that leverages decades-long in vivo and digital...
- This Cooperative Agreement award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $7,417,428 to Brigham & Women's Hospital, a subsidiary of the Partners Healthcare System, to develop a toolkit of 2D and 3D microphysiological systems (MPS) that capture human genetic diversity underlying risk and resilience to Alzheimer's disease (AD) and related dementias (ADRD). The award period is from July 1, 2025 to June 30, 2030. The project aims to leverage iPSC lines from...
- This $2,356,117 federal Project Grant award from the National Institute on Aging's Aging Research program (CFDA 93.866) will support research to improve the perioperative management of patients with Alzheimer's disease and related dementias. The primary objectives are to: (1) identify the extent to which surgical patients with these conditions are at increased risk for adverse postoperative outcomes, and (2) estimate the association between various perioperative interventions and the incidence...
- This $1,933,556 Project Grant awarded by the National Institute on Aging (NIA) under its Aging Research program (CFDA 93.866) will support research to assess the impact of hospital-based health information technology (hospital-HIT) on healthcare quality and equity for patients with Alzheimer's disease and related dementias (ADRD). The primary awardee, the University of Maryland, College Park, will conduct a ten-year longitudinal study to evaluate how hospital-HIT systems that promote care...
- This $375,840 Project Grant award from the National Science Foundation's (NSF) Computer and Information Science and Engineering (CISE) program (CFDA 47.070) supports the development of advanced machine learning models to enable accurate and early prediction of Alzheimer's disease and related dementias (ADRD). The project, led by the University of Virginia, will leverage novel natural language processing techniques to automatically extract personal risk factors for ADRD from electronic health...
- This $2,528,708 federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) supports research on the impact of undiagnosed Alzheimer's disease and related dementias (AD/ADRD) on healthcare utilization across geographic regions in the United States. The project will leverage Medicare claims data and cognitive assessment data from the REGARDS longitudinal cohort study to model the timeframe and consequences of undiagnosed AD/ADRD at the county and hospital...
- This federal Project Grant award of $402,750 from the National Institute of Environmental Health Sciences under the Medical Library Assistance program (CFDA 93.879) supports the development of large language models (LLMs) for drug safety and effectiveness causal analysis using real-world data from electronic health records (EHRs). The primary objective is to build an LLM-based causal analytical platform that can robustly determine a wide variety of clinical phenotypes, including those not...
- This federal Project Grant award of $150,000.00, funded by the National Science Foundation (NSF) under the Computer and Information Science and Engineering (CISE) program (CFDA 47.070), aims to develop advanced machine learning models and algorithms for the early prediction of Alzheimer's Disease and Related Dementias (ADRD) using electronic health record (EHR) data. The research project, led by the University of Iowa, will leverage natural language processing techniques to automatically extract...
This $3,687,278 federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) aims to optimize the validity of comparative effectiveness research in Alzheimer's disease and related dementias using large language models. The grant supports research at Brigham & Women's Hospital, a subsidiary of the Partners Healthcare System, to build novel large language models that can extract clinically relevant phenotypes from electronic health record data. This will enable more robust comparative effectiveness analyses for people living with dementia, who are vulnerable to medication issues but often underrepresented in randomized controlled trials. The project runs from September 2025 to September 2029 and involves integrating electronic health records with external geriatric datasets to train the language models on ADRD-relevant concepts and phenotypes.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $3.7m | 9/10/25 |