Project Grant RF1AG084104
- Federal Project Grant Award Summary New York University School of Medicine has been awarded $712,578 by the National Institute on Aging under the Aging Research program (CFDA 93.866) to conduct a prospective study examining the relationship between viral infections and Alzheimer's disease (AD) risk. The award, effective February 1, 2026, through December 31, 2030, will deliver a comprehensive longitudinal research investigation utilizing three prospective cohorts to identify viral infections...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded $3.28 million to Harvard T.H. Chan School of Public Health under the Aging Research program (CFDA 93.866) to conduct longitudinal epidemiological research examining the relationship between herpesvirus infection, immune responses, apolipoprotein E (APOE) genotype, and tau-pathology development in Alzheimer's disease (AD). The four-year project, initiated September 15, 2025 and concluding August 31, 2029,...
- This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) will support research at Virginia Commonwealth University (VCU) to investigate the effect of the trans-synaptic spread of pathogenic tau protein in the hippocampus and its impact on vulnerable neuron subtypes in Alzheimer's disease (AD). The $408,638 award, effective from August 1, 2024 to July 31, 2026, will involve the use of adeno-associated viral vector transfection, immunofluorescence, and...
- This Project Grant award from the National Institute on Aging (NIA), under the Aging Research program (CFDA 93.866), will fund research to investigate whether SARS-CoV-2 proteins can accelerate the development of Alzheimer's disease pathology in fly and mouse models. The $419,375 award to the University of Florida will support a 2-year study to screen SARS-CoV-2 proteins and assess their effects on Alzheimer's-related amyloid-beta aggregation and neurodegeneration. The research aims to elucidate...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded the University of North Carolina at Chapel Hill $420,119 on September 1, 2025, under the Aging Research program (CFDA 93.866) to support a two-year research project through August 31, 2027. This Project Grant funds the development of advanced computational models to understand tau aggregate propagation mechanisms in Alzheimer's disease. The research will produce a multi-layer neural transport equation that...
- Federal Project Grant Award Summary Baylor College of Medicine received a $3,039,032 Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866) awarded on August 15, 2025, with a completion date of July 31, 2029. The grant funds research investigating the relationship between SARS-CoV-2 (COVID-19) infection and the initiation and acceleration of Alzheimer's disease and related dementias (AD/RD), including Pick's disease, frontotemporal dementia, and other...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded the University of California, Irvine a Project Grant of $1,546,062 under the Aging Research program (CFDA 93.866) to conduct cell-type-specific and spatial proteogenomics analysis of aberrant RNA splicing and misfolded proteins in Alzheimer's-related tauopathies. The award, effective June 1, 2025, through March 31, 2030, supports a multi-investigator research initiative that will generate single-cell spatial...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded a $3.15 million Project Grant under the Aging Research program (CFDA 93.866) to The Regents of the University of California, San Francisco, effective June 1, 2025, through February 28, 2030. This research initiative, titled "Aberrant Proteomes in Tauopathy: Revealing Functional Consequences via Multimodal Proteomics," combines mass spectrometry-based proteomics and functional genomics expertise to...
- This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) totaling $433,125 will fund a study to investigate the relationship between microglia, neurons, and tau pathology in Alzheimer's disease. The research will utilize a novel model system of microglial co-cultures with hippocampal assembloids derived from patient-derived induced pluripotent stem cell (iPSC) lines with MAPT mutations and healthy controls. The goal is to explore how bidirectional changes...
- Federal Grant Award Summary The National Institute on Aging awarded a Project Grant of $1,112,821 to the University of Texas Medical Branch at Galveston under the Aging Research program (CFDA 93.866) beginning January 1, 2026 and concluding December 31, 2030. This research project will investigate the interplay between microglia and tau oligomer polymorphs in cognitive resilience among individuals with Alzheimer's Disease neuropathology. The research aims to identify protective mechanisms that...
The National Institute on Aging (NIA) awarded a $1,281,004 Project Grant under the Aging Research federal grant program (CFDA 93.866) to The University of North Carolina at Charlotte to investigate the interactions between viral infection, tau pathology, and neuroinflammation. The 3-year research project aims to determine whether viral infection increases tau pathology, assess the impact of tau aggregation on viral replication, and examine the effect of tau pathology on the neuroinflammatory response to viral infection. By establishing a mechanistic link between Alzheimer's disease and viral pathogens, this research seeks to expand the understanding of how environmental factors that increase neuroinflammation, including viral infections, may contribute to the development of Alzheimer's disease.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.3m | 8/23/23 |