Project Grant R61MH144575
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded the University of Chicago a Project Grant of $819,998 under the Mental Health Research Grants program (CFDA 93.242) on August 6, 2025, with a completion date of May 31, 2030. The grant funds "Basic Income Guarantee Chicago: A Trial of Basic Income," a randomized controlled trial examining the impact of unconditional cash transfers on young people living with HIV (YPLWH). The primary deliverables include:...
- Federal Grant Award Summary The University of Chicago received a $200,000 project grant awarded July 7, 2025, through the National Institute of Mental Health under the Mental Health Research Grants program (CFDA 93.242) to develop and test the PHARM ART (Pharmacy Technicians to Advance the Reach of Modern Antiretroviral Therapy) model. This implementation science research project will adapt and evaluate a pharmacy technician-based delivery model for long-acting injectable...
- Federal Grant Award Summary The University of Texas Southwestern Medical Center received a $837,097 Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), awarded September 22, 2025, with a completion date of May 31, 2030. This research project investigates microglial proliferation and its relationship to executive function and cognitive control in virally-suppressed people with human immunodeficiency virus (HIV). The...
- Federal Project Grant Award Summary Icahn School of Medicine at Mount Sinai received a $3.61 million Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), awarded on September 22, 2025, with a completion date of September 21, 2029. This four-year research initiative, titled "Targeting the NLRP3 Inflammasome to Mitigate Neuroinflammation and HIV Persistence in the CNS: Mechanisms and Therapeutic Strategies,"...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded the University of Rochester a $601,307 Project Grant effective September 24, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The research initiative, titled "Ribosomal Frameshifting in HIV-1 Infection, Inflammation and Neurotoxicity," will be conducted in Rochester, New York, with a completion date of June 30,...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded the University of Alabama at Birmingham $250,000 under the Mental Health Research Grants program (CFDA 93.242) on August 18, 2025, for a multi-project research program focused on developing novel cell and gene therapy approaches for HIV cure. The award funds research extending through June 30, 2030, and involves a well-integrated collaboration among multiple principal investigators including Dr. Goepfert, Drs....
- Federal Project Grant Award Summary Modulo Bio, Inc. received a $1.48M project grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), awarded on March 1, 2026, with completion targeted for February 29, 2028. The awardee will develop an artificial intelligence (AI)-guided triculture platform to model HIV-associated brain injury (HABI) under antiretroviral therapy (ART) suppression. The platform integrates induced pluripotent stem...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded $698,390 to the Regents of the University of California at Riverside under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) effective August 1, 2025, with completion anticipated by June 30, 2030. This Project Grant supports research into harnessing innate immune responses to control the neuroinflammatory human immunodeficiency virus (HIV)...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke awarded The Regents of the University of Colorado a $184,506 project grant effective August 7, 2025, through July 31, 2027, under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The research project investigates the dual roles of amyloid beta (Aβ) in central nervous system neuropathogenesis of HIV-associated neurocognitive disorder (HAND),...
- Federal Grant Award Summary Yale University received a $491,700 Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) awarded on September 3, 2025, with a completion date of September 2, 2027. The research project, titled "The Role of CSF Memory B Cells in Neuropathogenesis in PWH on ART," investigates the mechanisms of cognitive impairment in people with HIV (PWH) on antiretroviral therapy (ART) despite...
Rush University Medical Center received a $1.52M project grant from the National Institute of Mental Health under the Mental Health Research Grants program (CFDA 93.242), awarded April 1, 2026, with a completion date of March 31, 2028. The grant funds research utilizing a human-mouse chimera model to investigate the dynamics of HIV infection in the brain and its pathophysiological mechanisms. Specifically, the research examines how HIV-infected cells cross the blood-brain barrier, triggering inflammation and damage to resident brain cells, with the goal of better understanding HIV-Associated Neurocognitive Deficits (HAND) in patients receiving antiretroviral therapy (ART). The project delivers in vivo research services assessing the interactions between brain cells and peripheral immune cells in an HIV-infected, ART-treated model system. This basic science research aims to advance understanding of NeuroHIV pathogenesis in the contemporary ART era, when HAND typically manifests as mild to moderate neurological symptoms. The research is conducted at Rush University Medical Center's Chicago, Illinois location, an academic medical center with established expertise in HIV research and federal grant administration.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.5m | 3/16/26 |