Project Grant R56HD116739
- The federal Project Grant award of $660,773 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), will fund a research project titled "The Impact and Reversibility of Obesity-Induced Molecular and Functional Alterations to the Human Endometrium". The project, led by the Regents of the University of Michigan, aims to assess the impact of obesity on the...
- This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports a $716,192 research project to investigate the early transcriptomic changes associated with the development of endometriotic lesions. The project, running from September 2025 to August 2030, will integrate single-cell, spatial, and bulk transcriptomics analyses of peritoneal...
- This federal Project Grant award from the Defense Health Agency provides $1,555,000.00 to the University of North Carolina at Chapel Hill to support their research project titled "TARGETING OBESITY VIA DIET AND DRUGS FOR THE TREATMENT OF ENDOMETRIAL CANCER". The award is funded under the Military Medical Research and Development (CFDA 12.420) federal grant program, which supports advanced biomedical research initiatives focused on transforming healthcare for military personnel and...
- This National Cancer Institute (NCI) Project Grant award under the Cancer Biology Research program (CFDA 93.396) provides $456,103 in funding to The Feinstein Institutes for Medical Research to develop integrated risk models for endometrial cancer. The project aims to enhance early detection of endometrial cancer by determining the burden of rare genetic risk factors and creating predictive models that integrate genetic and non-genetic factors such as BMI, diabetes, and PCOS. The research will...
- This federal Project Grant award of $234,000 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to investigate the underlying mechanisms driving obesity and metabolic disorders in offspring of obese mothers. The research, conducted by Oregon Health & Science University, aims to leverage a mouse model to elucidate how maternal high-fat diet...
- This $448,441 federal Project Grant awarded by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) will support research at Emory University to investigate the role of mediobasal hypothalamic gliosis in gestational weight gain and visceral fat accretion. The primary aim is to provide foundational data on a potential neural mechanism underlying dysregulated or pathological weight gain during...
- The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) awarded a $161,735 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to the Metis Foundation, a non-profit research organization based in San Antonio, Texas. The funding will support a pilot feasibility study on a single-session, CBT-informed treatment for loss-of-control eating during pregnancy. The goal is to develop a brief, evidence-based intervention...
- This Project Grant award, valued at $643,049.00, was provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The grant supports the development of a physiomimetic model of endometrioma, a type of endometriotic lesion, to study processes driving lesion initiation, ovarian stroma invasion, and persistence in a chronic inflammatory environment. The research aims to uncover...
- This federal Project Grant award of $739,942 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to evaluate the impact of New York's Medicaid 1115 waiver on early childhood obesity risk in the New York City Health + Hospitals system. The key objectives are to: 1) Assess whether greater exposure to the waiver is associated with healthier infant...
- This Project Grant award, totaling $601,499 and spanning from June 2025 to May 2030, was provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The grant supports research focused on understanding how maternal obesity during pregnancy alters mitochondrial function in the offspring, which is linked to the later development of obesity and metabolic syndrome. Key objectives include:...
This federal Project Grant award of $1,394,304.00, awarded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research Program (CFDA 93.865), supports research to understand the relationship between obesity, endometrial hyperplasia, and endometrial cancer risk in women. The project, titled "Understanding Endometrial Tissue Field Defects in Obesity-Related Endometrial Hyperplasia", is a collaborative effort between Henry Ford Health and Michigan State University Health Sciences. The research aims to investigate the mechanisms by which obesity leads to hormonal imbalances and increased estrogen exposure, contributing to the development of endometrial hyperplasia and its potential progression to endometrial cancer. The 2-year project commenced on Sep 1, 2025 and is scheduled for completion by Aug 31, 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.4m | 8/29/25 |