Project Grant R21HD109652
Award Date
8/18/23
Completion Date
8/17/25
Dollars Obligated
$448K
Federal Agency
National Institute of Child Health and Human Development
Awardee
Emory University (S352L5PJLMP8)
Federal Grant Program
93.865
Assistance Type
Project Grant
Place of Performance
Decatur, GA 30033, USA
Similar Awards
This $624,000 Project Grant was awarded on August 1, 2024 by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The grant will fund a 2-year research project at the University of Michigan to investigate the impact of obesity and adiposity on the human endometrium. The key objectives are to: 1) use single-nuclear RNA sequencing to comprehensively understand how pathological adiposity...
This $660,773 Project Grant award, issued by the National Institute of Child Health and Human Development (CFDA 93.865 Child Health and Human Development Extramural Research program), will support research at the University of Michigan to assess the impact of obesity on the endometrium (uterine lining) and the reversibility of these changes with significant weight loss following bariatric surgery. The project aims to characterize the molecular, cellular, and functional alterations to the...
This federal Project Grant award, provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), aims to investigate the role of metabolic hormones, maternal obesity, and maternal exercise on the development of hippocampal synapses, which are strongly correlated with mental health outcomes. The key objectives are to: 1) Determine if insulin's neurotrophic actions are mediated by apelin,...
This $601,499 Project Grant was awarded on June 5, 2025 by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The grant supports research to investigate how maternal obesity alters mitochondrial function in the offspring, leading to the development of obesity and metabolic disorders later in life. The research focuses on examining the role of extracellular vesicles (EVs) released from...
The National Institute of Child Health and Human Development (NICHD) awarded a $427,625 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to The Washington University in St. Louis, Missouri. The grant aims to provide a mechanistic understanding of how maternal obesity affects uterine contractility and energy metabolism during labor and parturition. The researchers will use a mouse model of diet-induced obesity to investigate the impacts of excess fatty acids...
This $1,538,070.00 federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), will support research to investigate the role of mitochondrial nutrient transport in regulating trophoblast differentiation. The project aims to use CRISPR-Cas9 genetic tools to manipulate the expression of the mitochondrial pyruvate carrier (MPC) and glutamine transporter (SLC1A5VAR) in...
This Project Grant award, provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to better understand the biological mechanisms and early-life factors underlying childhood obesity and body composition in American Samoa. The $498,065.02 award, granted from August 1, 2024 to July 31, 2027, will utilize metabolomics and data from the Foafoaga O Le Ola Samoan infant...
The federal Project Grant award R21HD115119, totaling $531,174, was provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The grant aims to develop and test novel dual agonist therapies targeting the melanocortin and gut-peptide receptors for the treatment of childhood obesity. The research plan includes two specific aims: 1) fully characterizing and optimizing a GLP-1R/MC4R dual...
This federal Project Grant award from the National Institute of Child Health and Human Development, under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $148,568 to the University of Colorado-Denver to investigate the mechanism by which fetal glucagon regulates placental nutrient delivery. The goal is to identify how fetal glucagon acts to match placental nutrient supply to fetal metabolic demand, particularly in pregnancy complications involving...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will support research to investigate the neurobiological and behavioral underpinnings of intergenerational obesity in humans. The $585,232 award to Brigham & Women's Hospital Inc., a subsidiary of Partners Healthcare System Incorporated, will fund two complementary studies. The first study...