Project Grant R56DK146028
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the Board of Regents of Nevada System of Higher Education, operating as University of Nevada, Reno, $734,999 on September 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to investigate the molecular mechanisms of spinal cord injury-induced detrusor overactivity. The award funds research characterizing how apoptosis of platelet-derived growth factor receptor...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded $117,000 to The Regents Of The University Of Colorado on February 10, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to identify extracellular-vesicle-derived protein biomarkers for diabetic neuropathy. Diabetic neuropathy affects 50 percent of people with diabetes but lacks non-invasive clinical biomarkers to guide natural history studies and interventional trials....
- The National Institute of Diabetes and Digestive and Kidney Diseases, part of the Department of Health and Human Services National Institutes of Health, awarded Duke University $807,282 on May 11, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to investigate estrogen-dependent mechanisms modulating diabetic bladder dysfunction. The award funds research to determine how diabetes impacts the development and progression of overactive bladder...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the University of Houston System $167,696 on August 27, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to develop intelligent bioelectronic implants for diagnosis and neuromodulation of neurogenic bladder dysfunction. The award funds research to address urological dysfunction following spinal cord injury, particularly neurogenic bladder and detrusor sphincter...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded $713,227 to the University of Wisconsin–Madison on August 20, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847, Project Grant R01DK146259). The award funds research on the role of A-fiber mechanosensitive neurons in bladder function and urologic disease phenotypes, with focus on urologic chronic pelvic pain syndrome (UCPPS). The research team has developed new tools for...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the Regents of the University of Minnesota $694,934 on May 15, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to investigate modulation of interoception by TRPV1-expressing renal afferent nerves. The research addresses gaps in understanding afferent renal nerve location, origin, central nervous system interaction, and functional properties under physiological and...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded The Medical College of Wisconsin, Inc. $747,444 on September 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to investigate mechanisms and optimization of tibial nerve stimulation in treating neurogenic bladder dysfunction. The research maps neural connections between the tibial nerve and the lower urinary tract to understand how stimulating a nerve at the ankle...
- Federal Project Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded the University of Nevada, Reno a $2.56 million Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) effective September 15, 2025, with a completion date of September 14, 2029. This research award funds a four-year investigative project examining novel regulatory targets for gastrointestinal hormones and neuropeptides in...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the University of Virginia $797,878 on February 24, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to investigate the pathogenesis of concentric hypertrophy of kidney arterioles. The research examines how chronic stimulation of renin cells—triggered by renin-angiotensin system inhibitors or genetic mutations—leads to concentric arterial and arteriolar hypertrophy, a...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the Research Institute at Nationwide Children's Hospital $789,682 on August 25, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award funds research into the mechanisms by which the renal urothelium senses and responds to urinary tract obstruction and mitigates obstructive nephropathy. The project investigates how the renal urothelium undergoes remodeling during...
The National Institute of Diabetes and Digestive and Kidney Diseases awarded the Board of Regents of the University of Nebraska $250,000 on August 21, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The research examines autonomic dysfunction in diabetes via hypothalamic mechanisms and the role of renal nerves, specifically investigating how decreased neuronal nitric oxide synthase in the paraventricular nucleus contributes to erectile dysfunction in type 1 and type 2 diabetic rat models. The work addresses how altered central autonomic function may contribute to erectile dysfunction development in diabetes and proposes that increased renal afferent nerve activity activates a central pathway resulting in sympatho-excitation and erectile dysfunction. The project uses a renal denervation model to differentiate the contribution of reduced nitric oxide from the paraventricular nucleus versus reduced nitric oxide from peripheral nerves in erectile dysfunction development. The recipient is the University of Nebraska Medical Center in Omaha, Nebraska. Work is performed in Omaha, Nebraska. The period of performance extends from the award date through July 31, 2027. The assistance type is a Project Grant, obligating $250,000.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $250.0k | 8/24/26 |