This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), funded under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $655,971 to investigate the pathophysiological role of the brain's endogenous glucagon-like peptide 1 (GLP-1) system in the development of diet-induced obesity. The key objectives of this 5-year research project are to: 1) use electrophysiological, anatomical, and optical...
This $800,000 federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will support research at Beth Israel Deaconess Medical Center, Inc. (Bidmc) to develop new combinatorial pharmacology approaches for regulating multiple neuron types in the brain to effectively promote satiety and reduce body weight in mouse models of obesity. The research aims to...
This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will fund research to investigate the role of melanocortin peptides and their receptors in the medial prefrontal cortex on feeding behavior and obesity. The $499,761 award, effective from December 20, 2024 to November 20, 2029, will be executed by the Albert Einstein College of Medicine in...
This federal Project Grant award in the amount of $640,762.00 was issued by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award, with a start date of September 15, 2024 and an ultimate completion date of June 30, 2029, will fund research conducted by the Scripps Research Institute in La Jolla, California to investigate the interorgan communication mechanisms between...
The $441,000 Project Grant awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) will support research by the CAL Poly Pomona Foundation Inc. to identify a dopamine circuit in the brain that mediates day eating and diet-induced obesity in mice. The 3-year project seeks to genetically and anatomically define a subpopulation of dopaminergic neurons in the ventral tegmental...
This $595,858 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) will fund research conducted by the Regents of the University of Michigan to investigate the role of hypothalamic SH2B1 neurocircuits and SH2B1 signal transduction pathways in obesity and metabolic disease. The research aims to determine how SH2B1-expressing neurons in the paraventricular...
This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) provides $136,449 to The Regents of the University of California, Berkeley to evaluate the role of human obesity genes in specific neuronal populations using CRISPR-mediated gene downregulation. The goal is to rapidly test whether genes associated with obesity predisposition are required for the function of...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the CFDA program "Diabetes, Digestive, and Kidney Diseases Extramural Research" (93.847), will provide $340,175 to American University to conduct research on the effects of federal funding for obesity prevention programs on weight-related health behaviors, obesity prevalence, and obesity-related chronic conditions. The project aims to leverage variation in county and...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), awarded a $502,233 Project Grant to the Regents of the University of Michigan. The grant, awarded on February 1, 2025, with a completion date of November 30, 2029, will fund research to understand the neuron populations in the nucleus of the solitary tract (NTS) that mediate the aversive and non-aversive suppression of food...
This $107,250 federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) will support research to investigate the role of the nuclear receptor NR2F2 in driving the development of beige adipose tissue to protect against obesity. The research aims to elucidate how early-life exposure to high omega-6 fatty acids impacts adipose stem cell fate and...