The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), awarded a $502,233 Project Grant to the Regents of the University of Michigan. The grant, awarded on February 1, 2025, with a completion date of November 30, 2029, will fund research to understand the neuron populations in the nucleus of the solitary tract (NTS) that mediate the aversive and non-aversive suppression of food...
This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will fund research to investigate the role of melanocortin peptides and their receptors in the medial prefrontal cortex on feeding behavior and obesity. The $499,761 award, effective from December 20, 2024 to November 20, 2029, will be executed by the Albert Einstein College of Medicine in...
This $800,000 federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will support research at Beth Israel Deaconess Medical Center, Inc. (Bidmc) to develop new combinatorial pharmacology approaches for regulating multiple neuron types in the brain to effectively promote satiety and reduce body weight in mouse models of obesity. The research aims to...
This $1,040,519 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research at Arizona State University (ASU) to investigate the role of the epigenetic modifier JMJD3 in regulating hypothalamic leptin signaling and energy homeostasis. The key objectives are to: 1) Examine whether hypothalamic JMJD3 protects against obesity through an...
This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $176,500.00 to the University of Washington to investigate the links between hypothalamic microglia activation and perineuronal net (PNN) loss in the arcuate nucleus, and how these changes contribute to the pathogenesis of diet-induced obesity and glucose regulation. The...
This $576,810 Project Grant was awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant supports research at the University of Iowa to investigate the role of hypothalamic ciliary cAMP signaling in sex-specific regulation of metabolic homeostasis. The research aims to determine if the ciliary enzyme ADCY3 in ventromedial hypothalamic neurons is necessary for...
This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), funded under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $655,971 to investigate the pathophysiological role of the brain's endogenous glucagon-like peptide 1 (GLP-1) system in the development of diet-induced obesity. The key objectives of this 5-year research project are to: 1) use electrophysiological, anatomical, and optical...
The $441,000 Project Grant awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) will support research by the CAL Poly Pomona Foundation Inc. to identify a dopamine circuit in the brain that mediates day eating and diet-induced obesity in mice. The 3-year project seeks to genetically and anatomically define a subpopulation of dopaminergic neurons in the ventral tegmental...
This $241,130 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) supports research conducted by the Regents of the University of Michigan to study "Adaptive Response(s) to Complete Thyroglobulin Gene Knockout". The research aims to advance scientific understanding of disease mechanisms and develop new approaches for preventing, diagnosing,...
This federal Project Grant award in the amount of $640,762.00 was issued by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award, with a start date of September 15, 2024 and an ultimate completion date of June 30, 2029, will fund research conducted by the Scripps Research Institute in La Jolla, California to investigate the interorgan communication mechanisms between...