Project Grant R56DK139238
Award Date
9/15/24
Completion Date
8/31/26
Dollars Obligated
$644K
Similar Awards
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) totaling $1,384,487 will support research to explore the role of the hepatic lymphatic system in cholestatic liver diseases such as primary sclerosing cholangitis (PSC) and primary biliary cholangitis (PBC). The study aims to determine whether increasing lymphangiogenesis and lymphatic drainage could be a new therapeutic...
This federal Project Grant award of $1,198,646.00 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) supports research to understand the role of lysosomes, a key cellular organelle, in regulating intestinal stem cells and their contribution to intestinal tumorigenesis. The research aims to characterize how the transcription factors TFE3 and TFEB orchestrate the lysosomal...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $1,600,000 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to the Icahn School of Medicine at Mount Sinai. The project, titled "Decoding Endocrine and Paracrine Communication Through Mammokines," aims to discover new signaling molecules from the mammary gland that influence metabolic function and the progression of obesity and type 2...
This federal Project Grant award of $824,655 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The funding supports research at the University of Illinois to investigate the molecular and regulatory mechanisms by which growth hormone and sex-dependent transcription factors protect the liver from metabolic dysfunction-associated steatotic liver disease...
This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) supports a 5-year research program focused on defining novel neuro-immune pathways that regulate gut physiology. The $168,296 award to Weill Medical College of Cornell University aims to investigate the role of enzymes in group 3 innate lymphoid cells (ILC3s) and their impact on inflammatory bowel disease (IBD) and...
This $391,250 Project Grant awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) will support research on extracellular vesicle-dependent RNA signaling in metabolism. The project aims to identify key proteins involved in the delivery of adipose microRNAs into liver cells via extracellular vesicles, and to determine if this RNA delivery mechanism is necessary for...
This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $1,312,002.00 to the University of Illinois for a research project titled "Plasticity of Type 3 Innate Lymphoid Cells Regulated by Intestinal Microenvironment." The award period runs from June 1, 2025 to March 31, 2030. The key objectives of this research project are to:...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $603,632.00 to The Johns Hopkins University to conduct research on the role of the PLA2G12B protein in the assembly and metabolism of triglyceride-rich apolipoprotein B-containing lipoproteins. The research aims to elucidate the mechanisms by which PLA2G12B channels triglycerides into...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research to investigate the modulatory effects of the retinol-binding protein 2 (RBP2) on intestinal endocrine cells. The $166,644 award, made on September 1, 2024, will fund a 5-year project led by Dr. Rossana Calderon at Columbia University to: 1) determine the effects of RBP2 on the...
This Project Grant award for $108,000.00 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant aims to enable medical students at the Medical University of South Carolina (MUSC) to participate in high-quality research on gastrointestinal (GI) and liver diseases during their medical school training. Specifically, the grant will (1) provide a focused...