Project Grant R44DK136457

Award Date 9/17/24
Completion Date 6/30/27
Dollars Obligated $1.9M
Federal Grant Program
93.847
Assistance Type
Project Grant
Place of Performance
South Carolina, USA
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This Project Grant award of $3,740,270, provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports the development and evaluation of a subnormothermic (room temperature) oxygenated perfusion platform for extended preservation of high-risk kidney grafts. The awardee, Biomedinnovations, Inc. (BMI), is collaborating with investigators at the Duke Ex Vivo Organ Lab...
This Project Grant award of $134,852 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research) aims to develop a low-cost, non-destructive system called longitudinally detected electron paramagnetic resonance (LOD-EPR) to quantify and image iron oxide nanoparticles (IONPs) in cryopreserved rat kidneys. The goal is to optimize IONP perfusion, distribution, and radiofrequency heating parameters to improve...
The National Heart, Lung, and Blood Institute (NHLBI) awarded a $275,739 project grant under the Cardiovascular Diseases Research (CFDA 93.837) program to WR Biotech, LLC, a small disadvantaged business. The grant supports research on a novel technique called Improved Synchronization Modulation Electric Field (I-SMEF) to protect donor hearts and improve transplanted heart graft function during cold storage prior to heart transplantation in mice. The I-SMEF technique aims to maintain...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $748,049.00 to Rutgers, The State University of New Jersey, to conduct a multi-center validation and biological assessment of a novel pre-transplant biomarker panel to predict liver transplant recipient mortality. The project aims to advance the Liver Immune Frailty Index (LIFI) as an...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will support the development of a proteomic assay to monitor the success of regenerative medicine therapies involving cell replacement and artificial tissues, such as liver disease treatments. The $175,964 award to Hepatx Corporation will enable the creation of a simple blood test to measure the...
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