Project Grant R43DK139879
Award Date
5/13/25
Completion Date
4/30/27
Dollars Obligated
$176K
Federal Grant Program
93.847
Assistance Type
Project Grant
Place of Performance
Palo Alto, CA 94304, USA
Similar Awards
This $365,378 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) will support research on survivorship trajectories after liver transplantation. The primary objectives are to: 1) characterize distinct post-liver transplant survivorship phenotypes by mapping trajectories of patient-reported and clinical outcomes over time; 2) investigate the...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under CFDA 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research, provides $740,040 to Xylyx Bio, Inc. to develop and validate a liver fibrosis cell-based assay platform. The goal is to create an engineered in vitro model of human liver fibrotic lesions that integrates patient-derived stellate cells, Kupffer cells, and hepatocytes within a standardized fibrotic liver...
This $2,050,017 federal Project Grant was awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant, titled "Combating Chronic Liver Diseases via Understanding and Engineering Cell Competition and Fitness", aims to elucidate the mechanisms of cell competition in the liver and develop novel approaches for therapeutic cell transplantation to treat...
The University of Texas Southwestern Medical Center received a Project Grant award of $754,400.00 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award, with a start date of September 15, 2024 and an ultimate completion date of June 30, 2029, will support research to identify adaptive genetic pathways and understand the expansion of mutant clones within...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) will fund research to assess the use of extracellular vesicles (EVs) as biomarkers for predicting tacrolimus pharmacokinetics in liver transplant patients. The $385,250 grant awarded to the University of Florida will support a prospective clinical study to explore whether liver and gut-derived EV...
Amdx Prognostx Inc. received a $791,145 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases within the Department of Health and Human Services. The award falls under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), which promotes biomedical research to improve understanding and treatment of diabetes, digestive, and kidney diseases. Under this award, Amdx Prognostx will develop an enzyme-linked immunosorbent assay...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $443,432 Project Grant (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) to Michigan Technological University to develop liver organoids with integrated bile ducts for therapeutic applications. The objective is to evaluate and optimize the effects of patterned Notch signaling and biomechanical cues on co-cultured liver cells to create liver organoids with a functional bile-flow...
This $1,558,188 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under CFDA Program 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research supports research to investigate how changes in transcription factor and heterochromatin states impact liver development, homeostasis, and regeneration. The University of Pennsylvania is the prime awardee, collaborating with a sub-awardee, The Children's Hospital of Philadelphia, to...
This $200,000 federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) will fund a case-cohort study to identify novel determinants of living kidney donor risk. The study aims to improve the counseling and selection of living kidney donors by developing tools for tailored risk prediction based on donor characteristics. Key activities include conducting...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a Project Grant (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) in the amount of $143,968 to Brigham & Women's Hospital Inc., a subsidiary of Partners Healthcare System Incorporated, with an award date of December 19, 2024 and an ultimate completion date of November 30, 2026. The grant funding supports research aimed at early detection and treatment of hematopoietic stem cell...