Project Grant R44AG087855

Award Date 8/1/24
Completion Date 7/31/26
Dollars Obligated $1.2M
Federal Grant Program
93.866
Assistance Type
Project Grant
Place of Performance
Scarsdale, NY 10583, USA
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This Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) aims to develop advanced MRI techniques to directly assess cerebral microvascular pulsatility on widely available 3T MRI systems. The $4,692,540 award to Northwestern University will fund research to evaluate cerebral microvascular pulsatility as a potential biomarker for cerebral small vessel disease (CSVD), which is a major contributor to strokes and dementia. The project, running from August 2024 to...
This $1,246,362 project grant awarded by the National Institute on Aging (CFDA 93.866 - Aging Research) to Rush University Medical Center aims to elucidate the morphology and compositional changes of the perivascular pia mater (PVS PIA) in the human brain across aging and Alzheimer's disease. The 3-year project will leverage clinical and pathological data from the Rush Religious Orders Study and Memory and Aging Project to map PVS PIA anatomy using advanced microscopy techniques. Key...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) aims to create an inter-Alzheimer's Disease Research Center (ADRC) set of objectively measured cerebral small vessel disease (SVD) magnetic resonance imaging (MRI) biomarkers from large and diverse clinical cohorts. The $790,491 award will fund the development and validation of novel deep-learning methods to accurately quantify SVD biomarkers, including cerebral microbleeds, white matter...
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