This $1,361,648 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will support a multi-scale, multi-modal longitudinal imaging study to examine the association of cognitive function with changes in brain structure, function, and neuronal integrity in patients with multiple sclerosis (MS). The primary research objectives are to: 1)...
This $233,250 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program will fund research at The Washington University to investigate the potential of hyperpolarized 13C magnetic resonance spectroscopic imaging (HP 13C MRSI) and ultra-short echo time magnetization transfer (UTE-MT) imaging to non-invasively study the role of lactate metabolism and...
This federal Project Grant award, totaling $653,192.00 and provided by the National Institute of Neurological Disorders and Stroke (NINDS) under CFDA 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders, supports a longitudinal study on non-invasive imaging of pathological fibrin deposition and its effects on progressive neurodegeneration in the human brain. The study, conducted by the primary awardee The General Hospital Corporation (doing business as...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $541,109 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the University of Washington. The 5-year grant, beginning January 1, 2025, will fund research to quantify myelin loss and recovery in ischemic stroke patients using a novel magnetic resonance imaging (MRI) technique called single-point macromolecular proton fraction (MPF) mapping. The...
This $497,196 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program supports the development of a novel magnetic resonance spectroscopic imaging (MRSI) pulse sequence at 3 Tesla. The goal is to simultaneously map both downfield and upfield proton metabolic signals in the human brain, which may provide important new insights into brain metabolism....
This $538,523 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports the development of an innovative imaging and computational platform for integrated analysis of biodata. The platform aims to enable rapid and unbiased analysis of entire organs at subcellular resolution, with a focus on studying glial cell development in the mouse forebrain. The...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) provides $654,287 to the Icahn School of Medicine at Mount Sinai to conduct a study on cognitive impairment in multiple sclerosis (MS). The goal is to develop a psychometrically valid and biologically informed model of cognitive status in relapsing-remitting and progressive MS by...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $506,083.00 to Artificial Axon Labs Inc. to develop a novel biomimetic 3D-printed drug discovery platform called "Artificial Axons" for screening remyelinating compounds to treat multiple sclerosis (MS) and other myelin diseases. The key products and services...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $1,239,094 to the University of North Carolina at Chapel Hill to develop and optimize a rapid, robust quantitative magnetic resonance imaging (MRI) technique for high-resolution brain imaging. The project aims to leverage expertise in MRI fingerprinting, machine learning, and pulse...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) to Neuroscope Inc. in the amount of $1,193,370 aims to develop a computational toolset for mapping and quantifying perivascular space (PVS) morphology from MRI. The goal is to create a non-invasive, automated method to assess PVS, which is an important diagnostic feature for Alzheimer's disease and vascular dementia. The funded work will build the IT infrastructure to commercialize Neuroscope's PVS...