The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $497,196 Project Grant (CFDA 93.853) to The Johns Hopkins University to develop and evaluate new magnetic resonance spectroscopic imaging (MRSI) techniques for simultaneously mapping both upfield and downfield proton signals in the human brain at 3T. The project aims to create an improved pulse sequence for downfield MRSI with enhanced sensitivity and excitation profiles, and to establish the reproducibility and congruence of this new approach compared to conventional upfield MRSI. Additionally, the project will implement simultaneous upfield and downfield MRSI with optimal sensitivity, and continue to enhance the Osprey open-source MRSI post-processing software. The award period is from September 1, 2024 to June 30, 2028.
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