Project Grant R43HD120055
- This $380,692 Project Grant award from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) supports the development of an ultrapotent anti-sperm antibody construct for non-hormonal contraception. The project aims to create a non-hormonal, user-controlled contraceptive method based on an intravaginal ring that releases a highly effective anti-sperm antibody to agglutinate and trap sperm, preventing pregnancy. The...
- This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), funded under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports the development of a novel, non-hormonal contraceptive product, MM008. The $1,130,880 grant, awarded on September 15, 2025, will enable the awardee, Mucommune LLC, to formulate its proprietary anti-sperm monoclonal antibodies into fast-dissolving tablets for on-demand, non-hormonal...
- This $474,946 Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) supports the development of a novel, non-hormonal, female-initiated contraceptive device. The key products or services to be delivered under this grant include: Design and fabrication of a dual-compartment vaginal device that enables women to administer a polymeric, bioresponsive "smart fiber"...
- The National Institute of Child Health and Human Development (NICHD) awarded a $383,114 Small Business Innovation Research (SBIR) Phase I project grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to Venova Technologies Inc., a women-led and minority-led medical device startup company. The grant funds the development of a novel, non-hormonal, long-acting female contraceptive device designed to address the critical unmet need for birth control options without hormonal...
- The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) awarded a $561,097 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to Yale University. The grant supports research to understand the genetic basis and cellular/molecular mechanisms underlying reduced sperm motility, a major contributor to male infertility. Key objectives include leveraging Yale's access to large consanguineous Pakistani families with...
- This $306,872 Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under CFDA Program 93.865 Child Health and Human Development Extramural Research, is aimed at developing a sperm-specific epigenetic diagnostic test to predict the time it takes for couples to conceive. The award to Ripple Biosciences, LLC will leverage the company's existing sperm methylation data and machine learning pipeline, along with reproductive outcome...
- This federal Project Grant award of $356,502.00 was provided by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The funding supports PS-Fertility, Inc.'s development of a novel diagnostic test called PS-DETECT to quantify the potential fertilization-competent sperm in a semen sample. The goal is to refine this rapid assay and further the company's business model...
- The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) awarded a $613,556 Project Grant (CFDA 93.865) to Orygyn Medical Devices, LLC to develop a Tubal Selective Delivery System (TSDS). The TSDS is a novel device designed to safely and selectively administer fluids, foams, or gels to the fallopian tubes through a nonsurgical transcervical approach. This will provide clinicians with a simple and convenient office-based option to evaluate tubal occlusion during...
- This Project Grant award of $545,966 was provided by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The funding supports a Phase 1 first-in-human clinical trial conducted by Yaso Therapeutics Incorporated to evaluate the safety and pharmacokinetics of their YASO-GEL, a woman-controlled, on-demand vaginal gel that is both contraceptive and microbicidal. The trial...
- The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) awarded a $606,518 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to the Magee-Womens Research Institute and Foundation in Pittsburgh, Pennsylvania. The objective of this 5-year grant, awarded on June 5, 2025, is to test the safety and feasibility of transplanting human spermatogonial stem cells (hSSCs) or grafting testicular tissues back into patients...
The National Institute of Child Health and Human Development (NICHD), through its Child Health and Human Development Extramural Research program (CFDA 93.865), awarded a $399,999 Project Grant to Sacyl Pharmaceuticals, Inc. of Old Greenwich, CT. The grant aims to advance the development of a novel, on-demand, non-hormonal male contraceptive towards Investigational New Drug (IND) enablement. Sacyl Pharmaceuticals is developing small molecules that inhibit soluble adenylyl cyclase (ADCY10) in sperm, which has been genetically and pharmacologically validated as a target for male contraception. The 1-year project will fund activities to engage the FDA and progress the company's lead SAC inhibitor candidates through preclinical development. This award seeks to help address the significant unmet need for reliable and convenient contraceptive options for men, with the goal of reducing global unintended pregnancy rates.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $400.0k | 9/19/25 |