The National Institute of Child Health and Human Development (NICHD) awarded a $474,946 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to the University of Health Sciences and Pharmacy in St. Louis (UHSP) to develop a multipurpose device for female-initiated, non-steroidal, on-demand contraception. The project aims to create a drug-free, bioresponsive polymer-based vaginal device that can physically and chemically fortify natural...
This $518,754 Project Grant awarded by the National Institute of Child Health and Human Development under CFDA 93.865 (Child Health and Human Development Extramural Research) will fund the development of a bioadhesive vaginal film for extended release of multipurpose technology (MPT) antibodies. The project aims to create a vaginal film that combines a contraceptive monoclonal antibody (MAb) and MAbs against HIV and HSV, providing contraception and antiviral protection for 7 days following a...
This $291,440 Project Grant awarded by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) supports the development of ADAM AIR, a non-hormonal, reversible contraceptive device for men. The grant enables Contraline, Inc. to advance this technology, which leverages an injectable, long-lasting hydrogel to occlude the vas deferens and prevent sperm from reaching the ejaculatory duct. The ADAM...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $383,114 to Venova Technologies Inc., a minority-owned, women-led medical device startup, to advance the development of their novel, non-hormonal, long-acting female contraceptive device. The funding will enable Venova to continue improving and de-risking their innovative contraceptive technology...
This Project Grant award of $646,413.00 from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) supports preclinical development of serine/threonine kinase 33 (STK33) inhibitors as novel non-hormonal male contraceptive drugs. The funded research aims to identify potent, selective, and metabolically stable STK33 inhibitors, assess their pharmacokinetics and safety in mice and non-human primates, and evaluate their...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $841,397 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the Oak Crest Institute of Science to develop a novel, multi-compartment intravaginal ring for the prevention of genital herpes and unintended pregnancy.
The grant funded the integration of key innovations to create a next-generation multipurpose technology (MPT) intravaginal ring, including: (1) an antiviral peptide...
This federal Project Grant award of $742,966 from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) supports the development of a novel microwell device and deep learning framework to improve sperm identification and retrieval for men with azoospermia.
The key products and services to be delivered through this grant include:
A microwell device designed to digitize and confine cells from...
The National Institute of Child Health and Human Development (NICHD) awarded a Project Grant of $300,792.00 to Gynion, LLC on September 5, 2023 under the Child Health and Human Development Extramural Research program (CFDA 93.865). The funding will support the development and testing of MENORRX, a drug-device combination product intended to provide a non-invasive, cost-effective treatment for heavy menstrual bleeding (HMB). The proposed work aims to demonstrate the viability of the Yorkshire...
The University of Georgia Research Foundation, Inc. was awarded a $151,000 Project Grant from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) to study the role of uterine fluid dysregulation as a mechanism for hormonal contraceptives. The research aims to determine the time-course effects of the contraceptive compound RU486 on uterine fluid absorption during early pregnancy, as well as identify the fluid...
This Project Grant award for $658,633 was provided by the National Institute of Child Health and Human Development (NICHD) under the federal Child Health and Human Development Extramural Research program (CFDA 93.865) to study the role of the MEIG1 protein complex in sperm development and chromatin remodeling for normal embryogenesis.
The key products and services to be delivered include:
Dissecting the motor-based protein complex in the manchette structure of developing sperm and studying...