This $556,160 Project Grant awarded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (CFDA 93.846) aims to examine the efficacy of a rehabilitation approach called Rehabilitation with Exercise and Psychological Support (REPS) for patients who have undergone ACL reconstruction surgery. The REPS intervention integrates standard exercise rehabilitation with psychological support, including clinician training, patient education videos, and techniques like...
This National Institute on Aging (NIA) Project Grant award under the Aging Research program (CFDA 93.866) provides $308,927 to Tensense LLC, a small business located in Oregon, Wisconsin, to develop and evaluate an intraoperative sensor device to measure ligament engagement during total knee arthroplasty surgery. The key objectives of the project are to: 1) integrate a handheld ligament tensiometer into a custom joint distractor device and calibrate its ability to accurately measure ligament...
The National Institute on Aging (NIA), under the Aging Research Federal Grant Program (CFDA 93.866), awarded a $1,023,154 Project Grant (R01AG084683) to the University of Colorado-Denver to evaluate the effectiveness and implementation of neuromuscular electrical stimulation (NMES) in improving rehabilitation outcomes for patients who have undergone total knee arthroplasty (TKA). The study aims to compare outcomes between patients receiving contemporary rehabilitation with NMES versus usual...
The National Science Foundation (NSF) awarded a $274,997 Small Business Innovation Research (SBIR) Phase I Project Grant to Flex Orthopaedics, Inc. in Agoura Hills, CA. The grant supports the development of a novel ancillary orthopedic implant designed to increase the lifespan of total knee replacement devices. The project aims to prototype and validate a flexible tibial stem that can accommodate the multi-dimensional motion of the knee joint, reducing mechanical stress and wear on the primary...
The Defense Health Agency awarded a $1,401,588 Project Grant under the Military Medical Research and Development program (CFDA 12.420) to Roam Robotics Inc. to develop a unilateral powered knee orthosis for knee pain and instability intervention with the VA population. The award period runs from August 1, 2024 to January 31, 2026. Roam Robotics, a for-profit company that provides wearable robotics technologies, will leverage its expertise in exoskeleton systems and active knee assistance devices...
This federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), is intended to support the development of pre-operative planning software for the surgical treatment of patellar instability. The $292,954 award to Ortho Haus, LLC will fund work to generate data, validate computational models, and demonstrate proof-of-concept for a software platform that...
This Project Grant award from the National Institute on Aging's Aging Research Federal Grant Program (CFDA 93.866) provides $616,809 to the University of South Carolina to optimize a remote-based physical activity intervention for adults with total knee replacement. The goal is to identify the optimal combination of intervention components, including 0-4 supplemental non-automated components, to increase physical activity levels in this population. The primary aim is to determine which...
The National Science Foundation (NSF) awarded a $289,962 Project Grant under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program to The Cleveland Clinic Foundation, a non-profit academic medical center, to scope and plan the transformation of the "Open Knee(s)" open-source ecosystem for computational knee biomechanics research and innovation. The project aims to identify the infrastructure and operational prerequisites, leverage insights from other open-source...
The National Institute on Aging awarded a $639,997 Project Grant under the Aging Research program (CFDA 93.866) to The Spaulding Rehabilitation Hospital Corporation in Boston, MA. This 5-year grant, effective May 15, 2025, will fund research to investigate how physical exercise regulates molecular pathways in the knee joint to promote cartilage health and prevent osteoarthritis. The research will leverage advanced network medicine and single-cell analysis approaches to elucidate the mechanisms...
This federal Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) provides $613,744 to develop a lightweight, cost-effective telerehabilitation device. The device will provide motorized stretching and strengthening exercises for the knee joint, while restricting blood flow to enhance the benefits of low-load exercise for patients...