The National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), awarded a $1,800,418 Project Grant to Neuromuscular Dynamics LLC to clinically validate and enable a go-to-market strategy for their Leg Dexterity System. This patented, portable device is designed for home-based, short-latency sensorimotor neuromuscular training to help manage knee osteoarthritis (OA) through non-surgical means. The project will conduct a longitudinal, blinded trial comparing...
This federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under CFDA 93.846 - Arthritis, Musculoskeletal and Skin Diseases Research, provides $488,782 to conduct research on the use of neuromuscular electrical stimulation (NMES) to address quadriceps weakness and atrophy following anterior cruciate ligament (ACL) injury and reconstruction. The overarching objective is to establish the mechanistic basis for how NMES can mitigate the...
This Project Grant award from the National Institute on Aging (NIA), under the Aging Research program (CFDA 93.866), aims to develop an intraoperative sensor device to comprehensively measure ligament engagement during knee arthroplasty procedures. The total funding amount is $308,927 and the award period is from June 15, 2025 to May 31, 2026. The key objectives are to: 1) Integrate a handheld ligament tensiometer into a custom joint distractor to create an innovative "distraction...
This Project Grant award from the National Institute on Aging's Aging Research Federal Grant Program (CFDA 93.866) provides $616,809 to the University of South Carolina to optimize a remote-based physical activity intervention for adults with total knee replacement. The goal is to identify the optimal combination of intervention components, including 0-4 supplemental non-automated components, to increase physical activity levels in this population. The primary aim is to determine which...
This federal Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) aims to provide an integrated view of the complex pathophysiology of knee osteoarthritis (KOA) and mechanistically investigate how physiological exercise regulates molecular circuitry in cartilage and the surrounding knee joint in the setting of KOA. The award of $639,997 supports interdisciplinary research conducted by the Spaulding Rehabilitation Hospital Corporation to test the hypotheses that...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $903,697 to the University of Nebraska to conduct research aimed at improving rehabilitation outcomes for individuals with chronic ankle instability (CAI). The key objectives of the research are to: 1) determine functional and neurophysiological differences between subgroups of CAI patients, 2) evaluate the neurophysiological effects of a 4-week neurocognitively enhanced balance training...
This $299,820 federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), will fund a feasibility study on a telehealth-delivered mindful exercise intervention for people with knee osteoarthritis. The study aims to determine the feasibility of the mindful exercise program compared to telehealth-delivered exercise alone, as well as the feasibility of...
The National Institute on Aging (NIA), under the Aging Research program (CFDA 93.866), awarded a $1,193,500 project grant to the Lovelace Biomedical Research Institute. The grant will fund research to investigate the mechanisms by which transcranial electrical stimulation (TES) techniques, such as transcranial alternating current stimulation (TACS) and transcranial direct current stimulation (TDCS), modulate cerebral microcirculation and endothelial function. The project aims to differentiate...
This federal Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), provides $613,744 to Assistive Technology Development Inc. to develop a lightweight, robotic telerehabilitation device with integrated blood flow restriction for patients recovering from musculoskeletal conditions such as knee surgeries. The device aims to reduce the...
The National Institute on Aging (NIA) awarded a $2,617,270 Project Grant under the Aging Research (CFDA 93.866) program to Wake Forest University for the "A Mobile Health Behavior Intervention to Reduce Pain and Improve Health-III (MORPH-III)" project. This 5-year study aims to test the efficacy of a remotely delivered, group-mediated weight loss and increased physical activity intervention for reducing pain and improving health outcomes in older adults with chronic osteoarthritic knee...