Project Grant R21AR082572

Award Date 9/20/24
Completion Date 8/31/27
Dollars Obligated $556K
Federal Grant Program
93.846
Assistance Type
Project Grant
Place of Performance
Bloomington, MN 55425, USA
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This federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under CFDA 93.846 - Arthritis, Musculoskeletal and Skin Diseases Research, provides $488,782 to conduct research on the use of neuromuscular electrical stimulation (NMES) to address quadriceps weakness and atrophy following anterior cruciate ligament (ACL) injury and reconstruction. The overarching objective is to establish the mechanistic basis for how NMES can mitigate the...
This $147,236 federal Project Grant award was provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The funding supports a research project at the University of Pittsburgh to quantify the mechanical effects of knee bracing and assess its ability to prevent ligamentous injuries, such as to the medial collateral ligament (MCL) and anterior cruciate ligament (ACL). The...
This $520,154 Project Grant was awarded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The grant aims to determine the effects of non-invasive brain stimulation to improve quadriceps muscle function after anterior cruciate ligament (ACL) reconstruction. The research will administer anodal transcranial direct current stimulation (tDCS) to 42 female participants...
This $299,820 federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), will fund a feasibility study on a telehealth-delivered mindful exercise intervention for people with knee osteoarthritis. The study aims to determine the feasibility of the mindful exercise program compared to telehealth-delivered exercise alone, as well as the feasibility of...
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This $556,160 Project Grant awarded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (CFDA 93.846) aims to examine the efficacy of a rehabilitation approach called Rehabilitation with Exercise and Psychological Support (REPS) for patients who have undergone ACL reconstruction surgery.

The REPS intervention integrates standard exercise rehabilitation with psychological support, including clinician training, patient education videos, and techniques like cognitive-behavioral therapy. The pilot randomized controlled trial will enroll 60 ACL reconstruction patients to receive either REPS or standard rehabilitation, with the goal of improving psychological responses and knee function outcomes. Key expected deliverables include evaluating the feasibility, acceptability, and fidelity of implementing the REPS approach within clinical settings. The award period runs from Sep 2024 to Aug 2027 and is being conducted by the HealthPartners Institute in Bloomington, MN.

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