Project Grant R35GM161808
- Federal Grant Award Summary The University of California, San Diego received a $376,498 Project Grant from the National Institute of General Medical Sciences under the Biomedical Research and Research Training program (CFDA 93.859), effective August 1, 2025, through July 31, 2030. This award supports fundamental research into active genetic systems that function in both germline and somatic cell lineages. The research builds on established CRISPR-based genetic technologies that enable precise...
- Federal Project Grant Award Summary The University of California, San Diego received a $125,000 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective August 1, 2025, through July 31, 2027. This award supports fundamental research investigating the mechanisms of microtubule (MT) regulation at the cellular cortex, with the objective of elucidating how microtubule dynamics are...
- Federal Project Grant Award Summary The University of California, San Diego received a $327,019 Project Grant award dated July 25, 2025, from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The award supports research through April 30, 2030, focusing on developing innovative biophysical and computational frameworks to understand how cells transform during embryogenesis and stem cell differentiation. The...
- Federal Project Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded The Regents of the University of California, San Francisco a Project Grant totaling $380,070 under the Biomedical Research and Research Training program (CFDA 93.859) for the period July 1, 2025 through March 31, 2029. The award supports basic research investigating the cellular mechanisms of homologous chromosome pairing during meiosis, a fundamental biological process underlying Mendelian...
- Federal Project Grant Award Summary The University of California, San Diego received a $1.35M Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded September 5, 2025, with completion targeted for June 30, 2029. This award supports fundamental research to elucidate the molecular mechanisms by which Eukaryotic Initiation Factor 5A (EIF5A) influences mitochondrial function and cellular health....
- Federal Grant Award Summary The University of California, Merced received a $423,890 Project Grant from the National Institute of General Medical Sciences under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025, through May 31, 2030. This award supports fundamental research investigating the mechanisms of stem cell regulation during tissue renewal and cancer development, with a focus on understanding how stem cells survive DNA damage and acquire...
- Federal Project Grant Award Summary The University of California, Davis received a $431,614 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective August 1, 2025, through July 31, 2030. This fundamental research project investigates the biochemical and structural mechanisms regulating alpha/beta tubulin biogenesis and microtubule polymerization, with specific focus on how tubulin...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded a $299,452 Project Grant to the University of California, Davis on May 20, 2025, under the Biomedical Research and Research Training program (CFDA 93.859). The research project, titled "Identification of the Core Organizational Principles Within Nuclear mRNAs," will be conducted through December 31, 2027, at UC Davis's Davis, California campus. This fundamental biomedical research...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded UC San Diego a $347,086 Project Grant beginning September 1, 2025, and extending through August 31, 2030, under the Biomedical Research and Research Training program (CFDA 93.859). This award funds fundamental basic research to develop precision glyconanoassemblies through supramolecular design methodologies. The primary deliverable is the advancement of synthetic chemistry and molecular recognition...
- Federal Project Grant Award Summary The University of California, San Francisco received a $158,240 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective March 5, 2026, with completion targeted for November 30, 2027. This award supports investigator-initiated basic research aimed at elucidating the mechanical mechanisms by which E-cadherin regulates actomyosin network organization...
The University of California, San Diego received a $479,738 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective May 1, 2026, through April 30, 2031. This award supports fundamental research investigating the functions of kinetochore machinery—specialized protein complexes that control accurate chromosome segregation during cell division. The research addresses critical knowledge gaps in understanding how spindle structures communicate with kinetochores to regulate chromosome movement and prevent segregation errors that contribute to tumorigenesis, therapeutic resistance, and birth defects. The research project encompasses three primary focus areas: (1) investigating how spindle pole-localized kinase Aurora A and its activator TPXL1 regulate kinetochore-microtubule attachments to prevent spindle collapse; (2) conducting in vivo studies to evaluate newly discovered functions of chromosome segregation machinery in embryonic development; and (3) advancing understanding of the hierarchical assembly of kinetochores and their dynamic coupling mechanisms with microtubule polymers and motor proteins. Through this investigator-initiated research award, UCSD will generate foundational knowledge on cellular mechanisms essential for accurate genome inheritance and develop insights applicable to cancer biology and developmental biology.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $479.7k | 3/12/26 |