This federal Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences Program (CFDA 47.049) provides $149,926 to the University of California, San Diego (UC San Diego) to develop a comprehensive physical framework for understanding how avian embryos control their dynamic geometry during the critical developmental stage of gastrulation. The research aims to elucidate the fundamental cell behaviors and mechanical forces that shape the self-organized...
The National Institute of General Medical Sciences (NIGMS) awarded a $508,315 Project Grant (CFDA 93.859 - Biomedical Research and Research Training) to the University of California, San Diego (UCSD) to investigate the molecular mechanisms required for successful developmental progression from oocyte to embryo during a critical window of transcriptional silence in mammals. The overarching goal is to uncover post-transcriptional regulatory mechanisms, such as mRNA poly(A) tail dynamics, that...
This Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $393,093 to The Trustees of Columbia University in the City of New York to uncover the interplay between gene expression, cell morphometrics, and tissue-level mechanics during embryonic development. The research aims to develop an integrative, statistical machine learning framework for 4D mammalian development, leveraging...
This Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) provides $254,919 to the University of California, San Diego (UCSD) over a 5-year period from February 1, 2025 to January 31, 2030. The award supports research to understand the regulatory mechanisms that ensure accurate transmission of the genome during cell division. Key focus areas include investigating how cells prevent incomplete DNA...
This Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences (CFDA 47.049) program provides $227,747 to the Regents of the University of California at Riverside, a Hispanic-serving research institution, for a collaborative research project investigating morphogenesis and organ development. The key objectives of the funded research are to develop new multiscale mathematical and computational models to simulate multicellular wing disc morphogenesis in...
This Project Grant award, valued at $257,591, was provided by the National Science Foundation's (NSF) Division of Mathematical Sciences under the Mathematical and Physical Sciences (CFDA 47.049) federal grant program. The award supports a collaborative research project between the University of California-Riverside and the University of Notre Dame to develop data-driven, multi-scale mathematical and computational models for investigating the critical signaling pathways and biophysical mechanisms...
This Project Grant award for $509,982.00 was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The award supports research conducted by the University of Maryland, College Park to unravel the fundamental mechanisms governing cell-cell communication and signal exchange during animal development. The research aims to characterize a novel "direct delivery" mechanism of extracellular signal...
This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under CFDA Program 93.859 Biomedical Research and Research Training, is funding a research project titled "Investigating the Role of Signaling Feedback in Directed Cell Migration." The $147,656 award, with a project period from December 2024 to September 2027, will support investigations into the mechanisms by which cells regulate signaling pathways to control navigation during cell...
This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the federal Child Health and Human Development Extramural Research program (CFDA 93.865), provides $142,997 to the University Corporation at Monterey Bay to conduct research on the interaction between migrating cells and their substrate during tissue development. The key objectives are to investigate the role of BMP signaling in substrate morphogenesis driven by...
The National Institute of General Medical Sciences (NIGMS) awarded a $242,964 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to the University of Oregon. The award will support 2 years of fellowship training and research to understand the mechanisms of cell state transitions underlying organ size control during zebrafish fin regeneration. The research will leverage computational and quantitative imaging approaches to identify fibroblast-lineage cell...