Project Grant R35GM161174
- Federal Project Grant Award Summary Texas A&M Agrilife Research, the research division of the Texas A&M University System, received a $583,420 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025, through August 31, 2030. The award funds fundamental research to elucidate the role of protein conformational entropy (ΔSconf) in protein structural stability,...
- Federal Grant Award Summary Texas A&M University received a $392,812 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025 through June 30, 2028. The award supports the development and application of Bayesian statistical modeling approaches to analyze single-cell spatial transcriptomics data. The research investigates how circadian rhythm disruption (CRD)...
- Federal Project Grant Award Summary The University of Texas at Austin received a $429,650 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded April 6, 2026, with a completion date of March 31, 2031. This award supports fundamental research investigating the interplay between cellular metabolism, chromatin regulation, and transcriptional control in ethylene signaling and stress responses...
- Summary of Federal Project Grant Award Texas A&M University received a $375,929 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025, through August 31, 2030. The award supports a five-year fundamental research initiative investigating the epigenome-microbiome axis and its role in phenotypic plasticity using the purple sea urchin (Strongylocentrotus purpuratus) as a...
- Federal Grant Award Summary Texas A&M Engineering Experiment Station received a $135,000 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective May 4, 2026 through April 30, 2028. The award supports fundamental computational and biophysical research investigating the molecular mechanisms governing heterochromatin assembly through liquid-liquid phase separation (LLPS). The...
- Federal Project Grant Award Summary The University of Texas at Austin received a $270,208 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective April 1, 2026, through March 31, 2031. This award supports fundamental research investigating the molecular mechanisms and developmental control of PAR (partitioning-defective) polarity proteins in animal embryos, with particular focus on the...
- Federal Grant Award Summary Texas A&M Agrilife Research received a $416,398 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025, through June 30, 2030. This award supports fundamental research investigating the mechanisms and regulations of neutral lipid metabolism, specifically focusing on how cells synthesize and control the production of triacylglycerols and...
- Federal Project Grant Award Summary Texas State University received a $148,228 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective August 15, 2025 through June 30, 2029. The award funds fundamental biochemical research investigating the mechanism of protein sumoylation mediated by the SMC5/6 complex in DNA repair pathways. The research addresses a critical gap in understanding how...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded The University of Texas Health Science Center at San Antonio a $378,000 Project Grant effective May 1, 2026, through April 30, 2031, under the Biomedical Research and Research Training program (CFDA 93.859). This five-year project funds fundamental research investigating how intrinsically disordered proteins and intrinsically disordered regions regulate critical nuclear processes including...
- Federal Project Grant Award Summary Texas A&M University received a $950,000 Project Grant from the National Science Foundation (NSF) Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074), effective June 1, 2025 through May 31, 2029. The award supports fundamental research into the mechanisms of DNA demethylation, specifically investigating how the enzyme thymine DNA glycosylase (TDG) is targeted to specific methylated sites across the genome. The...
Texas A&M Agrilife Research received a $423,500 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective June 1, 2026, through February 28, 2031. This award supports fundamental research investigating the coordination of protein synthesis with cell division in budding yeast, a model organism that offers distinct experimental advantages for understanding cellular regulation mechanisms applicable to broader biological systems. The grant funds three integrated research projects designed to elucidate translational control mechanisms linking nutrient availability and metabolic cues to cell cycle progression. Project 1 examines how nutrient status regulates CAK1 (a CDK-activating kinase essential for cell division initiation), Project 2 investigates translational control of CLN3 (a G1 cyclin that commits cells to division) and identifies associated RNA-binding proteins, and Project 3 explores how translational regulation of ADE17 (critical for purine biosynthesis and one-carbon metabolism) influences cell cycle commitment. Collectively, these projects will advance understanding of how cells coordinate protein synthesis with proliferation signals, with implications for controlling aberrant cell proliferation in disease contexts.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $423.5k | 5/19/26 |