Project Grant R01GM163238
- This $380,089.00 federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), supports fundamental research on the molecular mechanisms underlying circadian rhythms. The project aims to determine the mechanisms that define the period and light-dependent phase shift of circadian rhythms, which are critical for aligning cellular and physiological processes with external environments. By...
- This $574,021 federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), aims to advance the scientific understanding of the molecular interconnections between circadian rhythms and lipid metabolism. The research project, led by the University of Missouri System, will investigate three key knowledge gaps: 1) how phosphatidic acid (PA) mediates nuclear processes, 2) how PA and lipid...
- This federal Project Grant award from the National Institute of General Medical Sciences (CFDA 93.859 Biomedical Research and Research Training program) provides $406,250 in funding to The Trustees of the University of Pennsylvania to conduct research on how circadian and metabolic rhythms regulate cell maturation and maintain cell maturity. The research will use in situ multimodal mapping of single-cell gene expression and functional states to determine how circadian clock transcription factors...
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) provides $361,454.00 in funding to the University of Massachusetts Boston to investigate the molecular mechanisms underlying circadian compensation in eukaryotic organisms. The overarching objectives are to: 1) define cellular effectors and metabolic variables that control circadian oscillations in fungi and test for...
- The federal Project Grant award of $999,784.00 from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) supports research on "Circadian Dysregulation as a Risk Factor for Age-Related Cognitive Impairment" at Texas A&M University System Health Science Center (TAMU HSC). The research aims to investigate the relationship between disruptions in the body's circadian rhythms and the development of age-related cognitive decline. TAMU...
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $451,250.00 to Children's Hospital Medical Center in Cincinnati, Ohio to investigate the molecular basis of circadian and sensory integration in neuronal clocks. The research aims to understand how gene expression in brain oscillators is affected when clock gene rhythms are disrupted in the suprachiasmatic nucleus,...
- This federal Project Grant award of $382,755.00 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), supports research to investigate the mechanisms underlying circadian gating of stress responses in plants. The project aims to leverage the Arabidopsis plant model and a combination of genetic, genomic, biochemical, and molecular biology approaches to identify key regulators involved in how the circadian...
- This federal Project Grant award of $837,277, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports research at Vanderbilt University to elucidate the fundamental cellular and molecular mechanisms of circadian entrainment and plasticity. The research aims to advance the understanding of how gene networks give rise to physiology, function, and behavior, with a focus on the brain's endogenous...
- This federal Project Grant award of $416,398 from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports fundamental scientific research on the regulation of neutral lipid metabolism in eukaryotes. The research program at Texas A&M AgriLife Research, a component of the Texas A&M University System, aims to elucidate the underlying mechanisms controlling the enzymatic activity of acyltransferases...
- The National Institute of General Medical Sciences (NIGMS) awarded a $435,126 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to the University of Chicago. The grant, titled "Connecting Circadian Clock Dynamics to Metabolism and Fitness," will support research to understand the biophysical basis of circadian rhythms and their connection to metabolism, with the goal of recreating an oscillatory system using purified components. Key activities...
This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $392,812.00 to Texas A&M University to conduct research on the effects of circadian rhythm disruption on the mammary microenvironment. The researchers will leverage spatial transcriptomics and Bayesian modeling approaches to investigate how disruptions to the body's 24-hour cycle impact cellular activities and pathways in mammary tissue. This research aims to provide insights into the molecular mechanisms linking circadian rhythm disruption to potential health impacts, such as increased risk of metabolic disorders, cardiovascular disease, and mood disorders. The award period runs from September 1, 2025 to June 30, 2028.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $392.8k | 8/25/25 |