Project Grant K99GM159055
- Federal Grant Award Summary Texas A&M University received a $392,812 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025 through June 30, 2028. The award supports the development and application of Bayesian statistical modeling approaches to analyze single-cell spatial transcriptomics data. The research investigates how circadian rhythm disruption (CRD)...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded The University of Texas Health Science Center at San Antonio a $378,000 Project Grant effective May 1, 2026, through April 30, 2031, under the Biomedical Research and Research Training program (CFDA 93.859). This five-year project funds fundamental research investigating how intrinsically disordered proteins and intrinsically disordered regions regulate critical nuclear processes including...
- Federal Project Grant Award Summary Texas State University received a $148,228 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective August 15, 2025 through June 30, 2029. The award funds fundamental biochemical research investigating the mechanism of protein sumoylation mediated by the SMC5/6 complex in DNA repair pathways. The research addresses a critical gap in understanding how...
- Federal Project Grant Award Summary Texas A&M Agrilife Research, the research division of the Texas A&M University System, received a $583,420 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025, through August 31, 2030. The award funds fundamental research to elucidate the role of protein conformational entropy (ΔSconf) in protein structural stability,...
- Federal Project Grant Award Summary The University of Texas at Austin received a $385,065 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 15, 2025, through August 31, 2030. This award supports fundamental research utilizing cryo-electron microscopy (cryo-EM) to elucidate the structure and function of macromolecular machines involved in gene regulation. The primary research...
- Federal Grant Award Summary Texas A&M Agrilife Research received a $416,398 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025, through June 30, 2030. This award supports fundamental research investigating the mechanisms and regulations of neutral lipid metabolism, specifically focusing on how cells synthesize and control the production of triacylglycerols and...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded $435,412 to the University of Houston System under the Biomedical Research and Research Training program (CFDA 93.859) for a two-year project commencing September 1, 2025. Principal Investigator Dr. Yu Liu will develop TO-Triplex-Seq, a novel whole-genome sequencing technology designed to identify and map RNA-DNA triple helix structures genome-wide. The technology leverages the differential affinity of...
- Summary of Federal Project Grant Award Texas A&M University received a $375,929 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025, through August 31, 2030. The award supports a five-year fundamental research initiative investigating the epigenome-microbiome axis and its role in phenotypic plasticity using the purple sea urchin (Strongylocentrotus purpuratus) as a...
- Federal Project Grant Award Summary Texas A&M Agrilife Research received a $423,500 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective June 1, 2026, through February 28, 2031. This award supports fundamental research investigating the coordination of protein synthesis with cell division in budding yeast, a model organism that offers distinct experimental advantages for...
- Federal Project Grant Award Summary Texas A&M University received a $950,000 Project Grant from the National Science Foundation (NSF) Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074), effective June 1, 2025 through May 31, 2029. The award supports fundamental research into the mechanisms of DNA demethylation, specifically investigating how the enzyme thymine DNA glycosylase (TDG) is targeted to specific methylated sites across the genome. The...
Texas A&M Engineering Experiment Station received a $135,000 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective May 4, 2026 through April 30, 2028. The award supports fundamental computational and biophysical research investigating the molecular mechanisms governing heterochromatin assembly through liquid-liquid phase separation (LLPS). The research focuses on characterizing the interactions between heterochromatin protein 1 (HP1) and other chromatin-associated proteins and nucleosomes to elucidate how these biological systems self-organize and regulate gene expression. The project delivers two primary research outputs: advanced computational models that elucidate the molecular drivers promoting co-phase separation of HP1 with associated proteins and DNA, and characterized biophysical interaction data between nucleosomes and heterochromatin constituent proteins. These research deliverables aim to establish foundational knowledge regarding heterochromatin dynamics and protein-DNA interactions, with potential applications toward understanding gene expression regulation and developing therapeutic interventions for chromatin dysfunction. The research is conducted at the awardee's facilities in College Station, Texas.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $135.0k | 5/5/26 |