Project Grant R35GM160174
- This federal Project Grant award, valued at $471,625.00, was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The grant supports fundamental scientific research and advanced training across diverse areas of biomedical science, with a focus on understanding biological processes and developing foundational knowledge for disease diagnosis, treatment, and prevention. The specific objectives of this award...
- This $251,573 federal project grant awarded by the National Science Foundation's Biological Sciences (CFDA 47.074) program aims to create the next generation of tools to enhance the utility of sea urchins as research models. The key products and services to be delivered under this 4-year award include: Developing simple and efficient protocols for culturing cells from sea urchin embryos to investigate gene function in vitro. Establishing rapid, scalable DNA transfection techniques for...
- This $199,919 Project Grant from the National Science Foundation Division of Ocean Sciences, under the Geosciences program (CFDA 47.050), will fund research by Sociedad Ambiente Marino Inc. on the causes and impacts of a resurgent die-off of the long-spined black sea urchin (Diadema antillarum) in the Caribbean. Using multidisciplinary approaches including metagenomics, metabolomics, and demographic analyses at four sites in Puerto Rico, the grantee will investigate the microbial profiles and...
- This federal Project Grant award for $380,540.00, provided by the National Institute of General Medical Sciences (NIGMS) under CFDA 93.859 - Biomedical Research and Research Training, supports research to investigate the relationship between DNA methylation and microRNAs during early human embryonic stem cell lineage specification. The research program seeks to dissect the early cell fate changes due to epigenetic regulation using omics technologies, cell imaging, and transcriptional regulator...
- This $300,072 Project Grant award from the National Science Foundation's Geosciences Program (CFDA 47.050) supports a collaborative research project to investigate the environmental drivers and impacts of Diadematidae scuticociliatosis, a disease affecting the long-spined sea urchin Diadema antillarum in the Caribbean. The research, led by the University of the Virgin Islands, combines field monitoring, laboratory experiments, and molecular analysis to understand how the pathogenic ciliate,...
- This federal Project Grant award, totaling $380,162.00, was provided by the National Science Foundation's Geosciences Program (CFDA 47.050) to the University of South Florida. The project, titled "Collaborative Research: Unraveling Parasite, Host, and Environmental Drivers of Diadematidae Scuticociliatosis, a Globally Significant Marine Disease," aims to investigate the environmental factors and microbiome interactions that influence the emergence and spread of a pathogenic ciliate...
- This National Science Foundation (NSF) Project Grant award under the Polar Programs (CFDA 47.078) provides $554,121 to the University of South Florida to study the ecology of an Antarctic sea squirt and its associated microbiome. The key objectives are to: Characterize the microbiome composition, metabolome, and mitochondrial DNA of the Antarctic sea squirt Synoicum adareanum at sites in the Antarctic Peninsula and McMurdo Sound. Use a multi-omics strategy to comprehensively examine the Synoicum...
- This federal Project Grant award, valued at $362,817.00 and funded by the National Science Foundation's (NSF) Polar Programs (CFDA 47.078), supports a collaborative research project to decode the microbiome diversity and potential function in the Antarctic pteropod Limacina rangii. The project, led by the Virginia Institute of Marine Science (VIMS), investigates the relationship between this key marine species and the specialized bacteria, called Mollicutes, that dominate its gut. By analyzing...
- This federal Project Grant award of $395,701.00 was provided by the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), to the University of Texas at Austin. The funding supports a research program to study the molecular bases of interactions between bacteria and between bacteria and their animal hosts, with a focus on insect microbiomes. The key objectives are to understand: 1) how competitive interactions between...
- The University of California, Merced received a $550,108 Project Grant award under the National Institute of General Medical Sciences' (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) to conduct fundamental research on the genetic regulation of microbial community formation, with a focus on biofilms. The project, which runs from May 5, 2025 to March 31, 2030, aims to provide new insights into the molecular and mechanistic bases of biofilm development, regulation, and...
This $375,929 federal Project Grant awarded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) will support a 5-year research project to study the relationship between the epigenome, microbiome, and phenotypic plasticity in the purple sea urchin. The research will profile natural microbial communities and conduct controlled experiments on early embryos to reveal how external microbes and the host epigenome interact to influence molecular and morphological phenotypes, and contribute to adaptive processes and phenotypic plasticity. The project will leverage the purple sea urchin as a model organism due to its large geographical range, evidence of local pH adaptation, and well-studied examples of adaptive phenotypic plasticity. The award was made to Texas A&M University, a public land-grant research institution with extensive expertise in delivering sophisticated scientific research and technical assistance to federal agencies.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $375.9k | 8/13/25 |