The National Institute of General Medical Sciences (NIGMS) awarded a $1,979,999 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to The New York Structural Biology Center, Inc. (NYSBC). The funding will be used to acquire a Bruker BioSpin Fast Shuttle System (FSS) apparatus to be installed on an existing 700 MHz NMR spectrometer at NYSBC. The FSS apparatus is a technological breakthrough that enables measurements of spin-lattice relaxation rate constants in...
The National Institute of General Medical Sciences (NIGMS) awarded a $1,048,299 Project Grant under the Biomedical Research and Research Training (CFDA 93.859) federal grant program to The Research Foundation for the State University of New York (RF-SUNY) on August 1, 2025. The funding will support the acquisition of a LUMICKS C-TRAP correlative force and fluorescence optical tweezer system, which will enable real-time observation, monitoring, and quantitation of interactions between...
This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) provides $335,712 to the University of New Mexico to develop advanced imaging techniques for studying protein interactions and organizations in cells. The primary objectives are to: 1) Develop high-resolution two-color single-particle tracking (SPT) methods to investigate dimer formation and dissociation, and 2) Create a...
This federal Project Grant award of $644,900.00, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports research on PAS (Period-ARNT-Single-Minded) domain proteins. The research aims to obtain mechanistic insights into how these ubiquitous signaling proteins, found across all kingdoms of life, detect and respond to changes in environmental conditions. Specifically, the research will utilize...
The National Institute of General Medical Sciences (NIGMS) has awarded a $389,653 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to The Research Foundation for the State University of New York (RF-SUNY), doing business as Rf-SUNY At The University At Albany. This 5-year project, starting on January 1, 2025, aims to develop a transdisciplinary research program centered around AI-supported biosensing and precision therapeutics using DNA nanotechnology and...
The National Institute of General Medical Sciences (NIGMS) has awarded a $294,147 Project Grant under the Biomedical Research and Research Training (CFDA 93.859) program to the University of Kansas Center for Research Inc. The 5-year grant, effective June 1, 2025, will support the development of advanced computational modeling approaches to characterize macromolecular interactions within living cells. The project aims to bridge classical docking and biomolecular simulation methods to enable...
The National Institute of General Medical Sciences (NIGMS) awarded a $344,400 Project Grant (CFDA 93.859 - Biomedical Research and Research Training) to The University of Texas Southwestern Medical Center to develop new tools and approaches for improving cryo-electron microscopy (cryo-EM) and cryo-electron tomography (cryo-ET) imaging techniques. Specifically, the grant aims to: 1) Develop a sample preparation strategy to reduce electron-induced radiolysis of frozen-hydrated biological...
This $1,444,500 Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) aims to develop new cryogenic electron microscopy (cryo-EM) methods to visualize the structural heterogeneity of ribosomes at the single-molecule level in cells. The award, effective September 2, 2024 through August 31, 2027, will enable the principal investigator to pursue strategies to extend a novel technique called 2D template...
This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training Program (CFDA 93.859) provides $278,848 to Brigham Young University to expand the capabilities and usage of the TELSAM protein crystallization chaperone. The funding supports research to develop experimentally validated guiding principles for the use of TELSAM, demonstrate its efficacy for a broad range of proteins, and showcase its applications and...
The National Institute of General Medical Sciences (NIGMS) awarded a $395,455 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Purdue University. The grant, effective August 1, 2025 through July 31, 2030, will support the development and application of computational methods for biomolecular structural modeling of cryo-electron microscopy (cryo-EM) data. Key objectives include enhancing structure modeling capabilities to improve accuracy and efficiency,...