Project Grant R35GM156876

Award Date 1/1/25
Completion Date 12/31/29
Dollars Obligated $316K
Federal Grant Program
93.859
Assistance Type
Project Grant
Place of Performance
Lawrence, KS 66045, USA
Similar Awards
This Project Grant award for $466,125.00 was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training federal grant program (CFDA 93.859). The award supports a research project at New York University School of Medicine to identify and characterize key metabolic control mechanisms, with a focus on understanding cellular mechanisms for sensing pyrimidine levels and iron availability. The project will develop cell and mouse models to...
This federal Project Grant award of $644,900.00, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports research on PAS (Period-ARNT-Single-Minded) domain proteins. The research aims to obtain mechanistic insights into how these ubiquitous signaling proteins, found across all kingdoms of life, detect and respond to changes in environmental conditions. Specifically, the research will utilize...
The National Institute of General Medical Sciences (NIGMS) awarded a $440,000 Project Grant (CFDA 93.859 - Biomedical Research and Research Training) to the Sloan-Kettering Institute for Cancer Research in New York. The 5-year grant, awarded on February 3, 2025, supports advanced research to decode the ubiquitin and autophagy signaling networks, which are essential cellular processes involved in proteome homeostasis. The research program combines expertise in quantitative mass spectrometry,...
The National Institute of General Medical Sciences (NIGMS) has awarded a $294,147 Project Grant under the Biomedical Research and Research Training (CFDA 93.859) program to the University of Kansas Center for Research Inc. The 5-year grant, effective June 1, 2025, will support the development of advanced computational modeling approaches to characterize macromolecular interactions within living cells. The project aims to bridge classical docking and biomolecular simulation methods to enable...
This Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) provides $609,493 to the Sloan-Kettering Institute for Cancer Research to conduct research on the molecular mechanisms underlying lipid and energy storage in cells. The award will fund studies to elucidate the structure, function, and cell biological roles of key enzymes and protein complexes involved in triacylglycerol synthesis and...
This Project Grant award, valued at $1,380,568.00 and provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training (CFDA 93.859) program, supports an interdisciplinary research initiative led by the University of Chicago. The project aims to develop a multiscale, predictive understanding of how cells adapt to changes in their environment, with potential applications in innovative therapeutic interventions for diseases. The research is...
This Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) provides $421,600 to The Morgridge Institute for Research, Inc. to understand how metabolic conditions influence the behavior of human cells. The key products and services to be delivered under this 5-year award include: Elucidating genetic and environmental contributions to human cell fitness and growth, leveraging innovative tools such as a...
This federal Project Grant award of $387,500.00 from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) supports research to determine the molecular mechanisms that regulate the activity of protein kinases. The research will use the Hippo pathway, which controls decisions of cell fate and number, as a model system to investigate different mechanisms that modulate the activity of protein kinases. The goal is to accelerate the...
This $145,642 federal Project Grant awarded by the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) will support research at William Marsh Rice University to investigate the role of autophagy inducers and peroxisomal proteins in pexophagy. The research aims to improve understanding of peroxisome regulation, which could have implications for metabolic illnesses in humans and metabolic engineering in crops. The key products or...
This federal Project Grant award, with ID R35GM154651, was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The $381,250 award, effective September 1, 2024 through August 31, 2029, will support research at the University of New Mexico Health Sciences Center (UNM HSC) to investigate the cellular mechanisms underlying the response to lysosomal damage. The research aims to establish the function of...

This Project Grant award for $316,368.00 was provided by the National Institute of General Medical Sciences (NIGMS), which administers the Biomedical Research and Research Training (CFDA 93.859) federal grant program.

The grant will fund research to understand the mechanisms of metabolic adaptation in cells, focusing on the autophagy and cytochrome P450 pathways. The research aims to elucidate how these pathways respond to nutrient scarcity and chemical stressors, using advanced genomics, microscopy, and proteomics techniques. The goal is to generate quantitative insights on metabolic adaptation from the single-molecule to the systems biology level, which could inform the development of more effective treatments for chronic diseases. The award period is from January 1, 2025 to December 31, 2029 and will be executed by the University of Kansas Center for Research Inc.

Generated 8/5/25, 6:09 AM