The National Institute of General Medical Sciences (NIGMS) awarded a $1,380,568 Project Grant under the Biomedical Research and Research Training Program (CFDA 93.859) to the University of Chicago. This 5-year grant, effective August 1, 2024, supports an interdisciplinary research project to develop a predictive, multi-scale understanding of how cells adapt to changes in their environment. The project has three main scientific thrusts: 1) Studying the adaptive roles of stress-induced biomolecular condensates in physiological adaptation, 2) Investigating how cells prioritize environmental responses at the transcriptomic level, and 3) Exploring the relationship between physiological and evolutionary adaptation. This integrated, multi-disciplinary approach aims to provide novel insights into maladaptive processes underlying aging, cancer, and neurodegeneration. The research will leverage techniques like single-cell transcriptomics and CRISPR screening to deliver these objectives.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $1.4m | 7/15/24 |