Project Grant R35GM156641
Award Date
7/1/25
Completion Date
4/30/30
Dollars Obligated
$385K
Federal Agency
National Institute of General Medical Sciences
Federal Grant Program
93.859
Assistance Type
Project Grant
Place of Performance
Columbia, MO 65211, USA
Similar Awards
The University of Missouri System was awarded a $357,666 Project Grant by the National Institute of General Medical Sciences (NIGMS), which administers the Biomedical Research and Research Training (CFDA 93.859) federal grant program. This 5-year grant, effective July 1, 2025, will support the university's research on the coordination of complex dynamics by DNA manipulating enzymes. Specifically, the project will use a combination of single-molecule techniques, including magnetic...
The U.S. National Institute of General Medical Sciences (NIGMS) awarded a $213,563.00 Project Grant (CFDA 93.859 - Biomedical Research and Research Training) to The Regents of the University of Colorado, effective September 5, 2024 through August 31, 2026. The grant funds research to develop a new class of "shape-shifting" cyclic peptides that can rapidly assume diverse structural isomers, allowing them to interact with multiple biological targets. The project aims to create a...
The National Institute of General Medical Sciences (NIGMS) awarded a $400,530 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to the Rector & Visitors of the University of Virginia (UVA) on June 1, 2025. The grant supports UVA's research to develop next-generation "nanodiscs" that can bypass limitations of traditional approaches for characterizing membrane proteins. This work aims to advance the understanding of how cell membranes regulate...
This $368,110 Project Grant awarded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports research to study the structures and properties of key enzymatic intermediates involved in oxygenase chemistry. The research aims to develop peptide-based synthetic models that can mimic the active sites and reactivity of non-heme iron and copper oxygenases, which are critical for metabolism, natural product...
This federal Project Grant award, identified as R35GM153303, was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The $1,189,314 grant, with a project period from September 1, 2024 to August 31, 2029, is focused on elucidating the roles of protein disaggregases and developing enhanced disaggregases to counter diverse protein-misfolding disorders. The research program at Washington University aims...
The National Institute of General Medical Sciences (NIGMS) awarded a $243,840 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to the University of Pittsburgh. The project, titled "An Effective Statistical Inference Framework to Develop Innovative Compensations for Protein Mutations," aims to develop quantitative methods for predicting the impact of protein mutations and identifying compensatory mutations that can restore normal protein...
This federal Project Grant award of $123,737.00 from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) supports research to advance drug discovery for protein domains containing intrinsically disordered regions. The award was granted to the Regents of the University of Michigan, a prominent U.S. state government-owned educational institution, with a performance period from October 1, 2024 to April 30, 2025. The NIGMS...
This Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training (CFDA 93.859) federal grant program, provides $124,767 to The Regents of the University of California, San Francisco (UCSF) to develop and test a pipeline for the de novo design of protein "enfolds" that can conditionally release cell-penetrating and antimicrobial peptides. The goal is to enhance the tissue specificity, stability, and therapeutic...
The National Institute of General Medical Sciences (NIGMS) awarded a $917,454 Project Grant under CFDA 93.859, Biomedical Research and Research Training, to Integral Molecular Inc. The grant supports the development of a novel Membrane Proteome Array (MPA) technology for specificity screening and profiling of biotherapeutics like monoclonal antibodies and CAR-T cell therapies. The MPA represents 93% of the human extracellular proteome expressed in native conformation, providing a more...
The National Institute of General Medical Sciences (NIGMS) awarded a $389,211 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to the University of Massachusetts (UMass) Amherst. The grant, which runs from July 2024 to June 2029, will fund research to investigate the biophysical and molecular mechanisms underlying a novel process of "meso-scale gap closure" in tissues undergoing epithelial-mesenchymal transition. The research aims to...