Project Grant R35GM155259
Award Date
9/1/24
Completion Date
8/31/29
Dollars Obligated
$410K
Funding Federal Agency
Assistant Secretary for Financial Resources
Awarding Federal Agency
National Institute of General Medical Sciences
Federal Grant Program
93.859
Assistance Type
Project Grant
Place of Performance
New Jersey, USA
Similar Awards
This Project Grant awarded by the National Institute of General Medical Sciences (NIGMS), under CFDA 93.859 Biomedical Research and Research Training Program, provides $410,000.00 in funding to The Trustees of Princeton University from September 1, 2024 to June 30, 2029. The award supports the university's theoretical and computational research to uncover the molecular determinants of biomolecular condensate compositional control and assembly mechanisms. The research program leverages...
This federal Project Grant award, valued at $445,873, was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The grant aims to characterize the composition, formation mechanism, and function of "non-canonical" stress granules induced by ultraviolet (UV) radiation, in contrast to the better-understood "canonical" stress granules formed under other stress conditions. The research will...
This federal Project Grant award, with ID R35GM154651, was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The $381,250 award, effective September 1, 2024 through August 31, 2029, will support research at the University of New Mexico Health Sciences Center (UNM HSC) to investigate the cellular mechanisms underlying the response to lysosomal damage. The research aims to establish the function of...
This Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), will provide $375,430 from February 1, 2025 to December 31, 2029 to the University of Wisconsin - Madison. The award will support research to investigate the regulation of RNA condensates, also known as membraneless organelles or RNA granules, by RNA helicases and their impact on biological processes during development. The...
This is a Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The $396,250 award to Vanderbilt University will support research to define the core biochemical principles underlying the spatial and temporal regulation of biomolecular condensates, using P granules in C. elegans embryogenesis as a model system. The key objectives are to: 1) identify biochemical determinants of P granule...
This $1,380,568 federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) supports an interdisciplinary research project at the University of Chicago. The project aims to develop a multiscale, predictive understanding of how cells adapt to changes in their environment across different timescales. The key research thrusts include studying the adaptive roles of stress-induced biomolecular condensates,...
This Project Grant award of $388,621 from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) will support the development of novel molecular designs with therapeutic potential. The key objectives are: Developing ligand-heterocycle conjugates as targeted RNA degraders with rapid kinetics and selectivity for cancer-associated G-quadruplexes. Engineering nucleic acid polymers with (thio)phosphoramidate backbones as biostable...
This federal Project Grant award of $372,880 from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) supports research to understand how cells regulate protein synthesis in response to environmental stressors. The award aims to investigate three key questions: 1) how the essential eIF2 translation initiation complex is formed, 2) the mechanisms by which eIF2 selects or disregards mRNAs for translation during the integrated...
The National Institute of General Medical Sciences (NIGMS) awarded a $1,218,750 Project Grant (CFDA 93.859 - Biomedical Research and Research Training) to The Trustees of the University of Pennsylvania, effective September 1, 2024. The funding will support the development of new bioorthogonal chemistries and protein-engineered biomaterials to enable independent and dynamic tuning of matrix stiffness, viscous force dissipation, and cell adhesive cues within 3D organotypic cell culture...
This federal Project Grant award of $337,949 from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) supports research to comprehensively classify and predict the function of intrinsically disordered protein regions. The University of Texas Southwestern Medical Center, the prime grantee, will use computational methods to categorize the modular sequence organization of disordered protein regions across different organisms....