The National Institute of Mental Health (NIMH) awarded a Project Grant under the Mental Health Research Grants program (CFDA 93.242) to The Trustees of Princeton University in the amount of $1,978,475. The award, with a period of performance from Aug 6, 2024 to Apr 30, 2029, supports research investigating the neural basis of visual attention in the primate brain. Key objectives include: (1) Establishing common behavioral patterns and relating them to intracranial neural activity in both...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372) provides $1,413,807.00 to Georgia TECH Research Corp, doing business as the Office of Sponsored Programs, to conduct research on tracking the flow of attention in visual circuits across the brain. The key objectives are to: 1) Establish the neural timing of...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Trustees of Columbia University in the City of New York, doing business as the Health Sciences Division, a $2,554,313 federal Project Grant under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372). The grant, which runs from Sep 1, 2023 to Aug 31, 2026, will support research to determine if targeted in vivo manipulations of local circuit control...
This Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) provides $443,671 to The Lieber Institute for Brain Development (LIBD) to investigate the molecular, cellular and circuit-level mechanisms underlying sustained attention deficits observed in neuropsychiatric disorders. The research leverages genetic and circuit-specific tools to dissect the role of the locus coeruleus-anterior cingulate cortex circuit and the...
This Project Grant award from the National Eye Institute (NEI), under the Vision Research federal grant program (CFDA 93.867), supports research to assess the spatial and temporal scales of attention effects and attention-dependent cholinergic release in the visual cortex of macaque monkeys. The $206,185 award, which runs from September 1, 2024 to March 31, 2027, will employ electrochemistry and electrophysiology techniques to test three competing models for the role of the neurotransmitter...
This Project Grant award of $910,000 from the National Science Foundation (NSF) Division of Behavioral and Cognitive Sciences supports research on the "Mechanisms of Willed Attention" at the University of California, Davis (UC Davis). This research, under the NSF's Social, Behavioral, and Economic Sciences program (CFDA 47.075), aims to investigate the brain mechanisms that enable humans to voluntarily direct their attention, especially in the absence of external cues. Using...
This Project Grant award, totaling $1,650,642.00, was provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242). The award, effective September 1, 2024, supports research to elucidate the role of basal forebrain parvalbumin-expressing GABAergic neurons in sustaining attention, a cognitive function often impaired in mental health disorders. The research aims to map these neuron projections, assess their dynamics during attention...
This $125,734 Project Grant award from the National Eye Institute (NEI), under the Vision Research program (CFDA 93.867), supports research to understand how distinct subregions of the prefrontal cortex modulate visual attention and processing in the visual cortex. The key objectives are to: Quantify and compare the activity of the anterior cingulate cortex (ACA) and orbitofrontal cortex (ORB) axons in the visual cortex during different stages of visual attention. Evaluate how perturbing the...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), supports research aimed at understanding the neural substrates of context-dependent decision-making in mice. The $252,125 award, spanning September 2024 to March 2028, will leverage whole-brain functional magnetic resonance imaging (fMRI) and advanced optogenetic techniques to: 1) identify brain regions involved in the maintenance of contextual information,...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $252,666 to The Trustees of Columbia University in the City of New York to conduct research on the role of functional modularity in the neural code underlying contextual behavior. The award will fund a combination of mathematical theory, artificial neural network modeling, and...