Project Grant R01MH137624

Award Date 8/6/24
Completion Date 4/30/29
Dollars Obligated $2M
Federal Grant Program
93.242
Assistance Type
Project Grant
Place of Performance
Princeton, NJ, USA
Similar Awards
The National Institute of Mental Health (NIMH) awarded a $823,252 Project Grant (CFDA 93.242) to The Trustees of Princeton University on September 18, 2024. The grant supports a 5-year research project titled "CROSS-BRAIN, MULTI-REGION INTERACTIONS IN DECISION FORMATION AND DECISION COMMITMENT" to investigate the neural mechanisms underlying decision-making processes. The project will be conducted at Princeton University and include a $134,987 sub-award to The Johns Hopkins...
This $2,153,762 Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports research to validate electrophysiological biomarkers associated with performance in a preclinical assay of sustained attention. The primary objectives are to optimize a rodent continuous performance test (rCPT) to study the impact of target percentage on vigilance decrement, evaluate the optimized rCPT using the stimulant amphetamine,...
This federal Project Grant award, provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), supports the development of a novel technique to selectively manipulate neural activity in the primate prefrontal cortex. The $431,750 award, granted on June 1, 2024, will be used by Rutgers, The State University to validate and refine this method using a primate economic decision paradigm. The goal is to modulate the subspace of neural...
This federal Project Grant award of $582,487, awarded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), aims to investigate the circuit and behavioral roles of parvalbumin-expressing GABAergic neurons in the basal forebrain to support sustained attention. The objective is to determine how this understudied basal forebrain neuron population contributes to cognitive functions like sustained attention, distinct from the known roles of...
The federal Project Grant award K99MH137314, totaling $127,305, was provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242). The award is supporting research by the Icahn School of Medicine at Mount Sinai to investigate the role of frontal parvalbumin interneuron maturation in the development of attentional abilities from adolescence to adulthood. The research aims to characterize how the maturation of these specific neurons in the...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372), will support research to investigate the biological mechanisms underlying attention control and information processing. The $864,475 award will enable The Trustees of Columbia University in the City of New York to: Provide behavioral evidence for the...
The National Institute of Mental Health (NIMH) awarded a $267,310 Project Grant (CFDA 93.242 - Mental Health Research Grants) to Trustees of Boston University's Medical Campus to study inhibitory neurotransmission in the prefrontal cortex of rhesus macaques. The research aims to understand how compartment-specific inhibition and laminar circuit dynamics in the lateral prefrontal cortex (LPFC) and anterior cingulate cortex (ACC) contribute to cognitive and emotional disturbances in...
This Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) provides $417,200.00 to Emory University to conduct research on characterizing and manipulating large-scale brain activity patterns. The key objectives are to: Use simultaneous wide-field optical imaging and functional MRI to determine if the distribution of quasi-periodic patterns (QPPs) in intrinsic brain activity reflects underlying neural activity...
This federal Project Grant award, issued by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), is funding research to investigate the neural mechanisms underlying social information processing and representation. The total award amount is $829,966.00 over the project period from August 16, 2024 to May 31, 2029. The research aims to elucidate how diverse social information, such as familiarity and hierarchy, is integrated in the brain...
This Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) provides $443,671 to The Lieber Institute for Brain Development (LIBD) to investigate the molecular, cellular and circuit-level mechanisms underlying sustained attention deficits observed in neuropsychiatric disorders. The research leverages genetic and circuit-specific tools to dissect the role of the locus coeruleus-anterior cingulate cortex circuit and the...

The National Institute of Mental Health (NIMH) awarded a $1,978,475 Project Grant (CFDA 93.242 - Mental Health Research Grants) to The Trustees of Princeton University to study the neural basis of visual attention in the primate brain. The grant, with an award date of August 6, 2024 and ultimate completion date of April 30, 2029, will investigate the temporal dynamics and neural mechanisms underlying visual attention, including how low-frequency rhythms coordinate sensory and motor processes. The research will be conducted using identical attention tasks in both humans and macaques, relating intracranial neural activity to behavioral outcomes across species. The project aims to establish common behavioral patterns and link them to neural population dynamics, bridging the gap between human and animal models. A sub-award of $816,832 was provided to the University of California, Berkeley to support specific aspects of the neural basis research.

Generated 5/13/25, 2:10 AM