Project Grant R35GM162707
- Federal Grant Award Summary The University of Virginia received a $425,145 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded March 1, 2026, with completion targeted for February 28, 2031. This award funds the development of integrated microscopy and image processing technologies to enable non-invasive, long-term three-dimensional (3D) fluorescence imaging of bacterial biofilm...
- Federal Grant Award Summary The University of Virginia received a $1,092,610 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded on March 15, 2026, with completion targeted for February 28, 2030. The grant funds development of an Impedance-Activated Recognition, Tracking, and Sorting (IARTS) system designed to enable near-real-time, label-free identification and isolation of...
- Federal Grant Award Summary The University of Virginia received a $415,171 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective March 15, 2026, through February 28, 2031. The award supports research to design and develop the first hydrogel three-dimensional (3D) cell culture platform with photopatterned spatiotemporal control of viscoelasticity and stress relaxation. This...
- Federal Grant Award Summary The University of Virginia received a $395,698 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded February 15, 2026, with a completion date of January 31, 2031. The award funds research investigating how the structural complexity of stem cell niches enables their regulatory function during development and homeostasis. The research utilizes the Caenorhabditis...
- Federal Grant Award Summary The University of Virginia received a $353,430 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 15, 2025, through July 31, 2029. This research project focuses on investigating the regulation of ceramide-1-phosphate (C1P) metabolism in cellular signaling networks, specifically examining how C1P facilitates metabolic reprogramming in response...
- Federal Project Grant Award Summary The University of Virginia received $888,250 in funding from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) to support research on protein sorting and localization to organelles. The award, effective August 1, 2025, through June 30, 2030, funds research investigating the molecular mechanisms governing protein import to mitochondrial and endoplasmic reticulum (ER) membranes....
- Federal Grant Award Summary The University of Virginia received a $444,125 Project Grant from the National Institute of General Medical Sciences under the Biomedical Research and Research Training program (CFDA 93.859), effective March 1, 2026 through February 28, 2031. The award supports fundamental research to elucidate the mechanisms of genome integrity maintenance, specifically investigating break-induced replication (BIR) at repetitive DNA sequences with a focus on alternative lengthening...
- Federal Grant Award Summary The University of Virginia received a $2,228,421 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective July 1, 2025, through June 30, 2030. The award funds the University of Virginia Medical Scientist Training Program (MSTP), which trains the next generation of biomedical scientists and physician-scientists through an integrated MD/PhD curriculum. The...
- Federal Project Grant Award Summary Clemson University received a $349,615 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective August 1, 2025 through May 31, 2030. The award supports the development of advanced imaging tools and data analysis methodologies for single-particle tracking (SPT) and single molecule localization microscopy (SMLM) to enable high-resolution study of protein...
- Federal Grant Award Summary The University of Virginia received a $642,028 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective July 1, 2025 through June 30, 2030. The Molecular Biophysics Training Grant (MBTG) program will provide comprehensive graduate student training to develop the next generation of biophysicists capable of conducting interdisciplinary research at the...
The University of Virginia received a $444,125 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective July 1, 2026 through April 30, 2031. The award funds development and implementation of Spatiotemporal Multiplexed Antigen Revealing Technology (SMART), an innovative imaging platform designed to enable longitudinal, nondestructive observation of dynamic cellular changes within live tissue and in vivo environments. The technology leverages CRISPR-Cas9 enzyme functionality to sequentially reveal and remove immunofluorescent signals through multiple imaging cycles, overcoming the spectral multiplexing limitations inherent in traditional intravital microscopy approaches. The research deliverables include synthesis of a comprehensive biomarker probe panel capable of profiling up to 20 distinct antigens and development of broad-impact applications for multiparameter phenotyping of living cells and multiplexed imaging of stem cell functional differentiation. Building on preliminary data demonstrating successful cycled immunofluorescence signal activation and deactivation at the cellular level, this project will generate unprecedented quantitative and qualitative data regarding dynamic cellular composition and functional evolution in complex tissue environments, advancing fundamental understanding of developmental and pathological processes while establishing a versatile platform applicable across multiple biomedical research domains.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $444.1k | 6/19/26 |