Project Grant R25CA314938
- The National Cancer Institute awarded Cold Spring Harbor Laboratory $105,020 on August 15, 2026, under the Cancer Research Manpower program (CFDA 93.398) to continue a seven-day intensive summer course on pancreatic cancer at the Banbury Center in Cold Spring Harbor, New York. The course serves medical and graduate students, postdoctoral fellows, and established investigators with a comprehensive curriculum covering organ anatomy and physiology, clinical diagnosis and treatment, molecular...
- The National Cancer Institute awarded the Regents of the University of Minnesota $309,761 on May 1, 2026, under the Cancer Research Manpower program (CFDA 93.398) to develop and deliver a hands-on training course in biomarker development and applications for cancer prevention research. The course combines virtual modules on chemical carcinogenesis fundamentals with five weeks of in-person laboratory training in state-of-the-art biomarker measurement techniques at the Masonic Cancer Center....
- The National Institutes of Health National Cancer Institute awarded Cold Spring Harbor Laboratory $793,679 on August 6, 2026, under the Cancer Biology Research program (CFDA 93.396) to develop whole-body redox maps for metastatic cancer therapy. The project uses protein degradation-based sensing to visualize oxidative stress in vivo across animal models of prostate cancer. The work generates two complementary, immune-competent mouse models—OXIGEM and ROXYCAP—that reveal cellular redox states...
- The National Cancer Institute awarded the Beckman Research Institute of the City of Hope $162,000 on August 11, 2026, under the Cancer Research Manpower program (CFDA 93.398) to develop and pilot a self-directed e-learning delivery model for clinical cancer genomics education. The recipient will convert selected core recorded didactic modules from its established Intensive Course in Clinical Cancer Genomics into a self-directed e-learning course bundle using theoretically grounded...
- The National Cancer Institute awarded the University of Massachusetts Medical School $111,645 under the Cancer Research Manpower program (CFDA 93.398) on January 1, 2026, to support research training in basic and clinical cancer research. The award funds investigation of the functional role of CAMK2B loss in pancreatic cancer metastasis, examining how deletion of the calcium/calmodulin-dependent protein kinase II beta gene enhances tumor metastasis and creates an immunosuppressive tumor...
- The National Cancer Institute awarded Cold Spring Harbor Laboratory $770,911 under the Cancer Biology Research program (CFDA 93.396) on July 1, 2026, to define the role of sphingolipid synthesis in anti-tumor immunity. The project investigates how alterations in lipid metabolism, particularly sphingolipid synthesis catalyzed by serine palmitoyl transferase (SPT), enable cancer cells to evade immune attack in the tumor microenvironment. Preliminary in vivo genetic screens in KRAS-mutant mouse...
- The National Cancer Institute awarded Cold Spring Harbor Laboratory $704,182 under the Cancer Biology Research program (CFDA 93.396) on June 16, 2026, to dissect non-mutational mechanisms driving benign-to-malignant transition in colorectal cancer. The project uses a novel mouse model that stepwise acquires mutations mirroring human colorectal cancer progression—starting with APC knockout to initiate benign polyps, then inducing KRAS G12V and TP53 loss in rare cells within established polyps...
- The National Institute of Environmental Health Sciences awarded New York University School of Medicine $228,825 on June 15, 2026, under the Medical Library Assistance program (CFDA 93.879) to develop computational and experimental frameworks for integrated analysis of spatial metabolomics and transcriptomics datasets in cancer biology. The work addresses the integration of spatial transcriptomics (ST) and spatial metabolomics (SM) by mass spectrometry imaging to map cellular states and drug...
- The National Cancer Institute awarded The Rockefeller University $559,596 on July 1, 2026, for research identifying metabolic vulnerabilities in liver cancer under the Cancer Biology Research program (CFDA 93.396). The funded research characterizes mitochondrial metabolites that drive hepatocellular carcinoma and other primary liver cancers through a rapid organelle immunopurification technique (MITO-IP) coupled with liquid chromatography–mass spectrometry. Preliminary work identified marked...
- The National Cancer Institute awarded Yale University $226,884 under the Cancer Research Manpower program (CFDA 93.398) on January 16, 2026, to support research training in cancer science. The award funds investigation into the role of aberrant m5C mRNA modification in translation initiation and cancer, with the recipient conducting screening of approximately 35,000 human endogenous 5′-untranslated region sequences from multiple tissues to identify m5C installation targets by NSUN2 and NSUN6...
The National Cancer Institute awarded Cold Spring Harbor Laboratory $199,573 on September 1, 2026, under the Cancer Research Manpower program (CFDA 93.398) to deliver an intensive sixteen-day laboratory and lecture course on metabolomics, held annually each summer from 2026 through 2030. The course combines theoretical instruction and hands-on training in cutting-edge metabolomics approaches to interrogate biochemical state. Metabolomics is a systems-biology technology that simultaneously monitors and characterizes hundreds or thousands of intracellular and extracellular metabolites, enabling researchers to probe biological processes in parallel alongside genomics and proteomics. The training addresses applications across diverse model systems—mammalian (mouse, zebrafish, rat, frog), invertebrate (worms, flies), and emerging stem-cell and organoid technologies—with particular focus on cancer metabolism, where tumor cells undergo metabolic reprogramming that drives survival, progression, metastasis, and therapy resistance while reshaping metabolic pathways in the surrounding microenvironment. Performance occurs at Cold Spring Harbor Laboratory in Cold Spring Harbor, New York. The award period runs from September 1, 2026, through August 31, 2031. The Cancer Research Manpower program supports biomedical training opportunities for individuals pursuing careers in basic, clinical, and prevention research relevant to the National Cancer Program, with grants awarded for up to five years to nonprofit and for-profit institutions capable of providing staff, facilities, and trainee selection.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $199.6k | 8/11/26 |