Project Grant R25CA306814
- Federal Grant Award Summary The National Cancer Institute awarded a $105,189 Project Grant to the Regents of the University of Minnesota under the Cancer Research Manpower program (CFDA 93.398) effective December 1, 2025, with completion targeted for June 30, 2027. This award funds research aimed at deciphering the structural dynamics and inhibition mechanisms of APOBEC3A (A3A) and APOBEC3B (A3B) enzymes, which play dual roles in host antiviral defense and genomic stability while contributing to...
- Federal Project Grant Award Summary The National Cancer Institute awarded $395,973 to the University of Minnesota (Regents of the University of Minnesota) under the Cancer Treatment Research program (CFDA 93.395) for a project focused on developing deazaflavin analogs as selective multidrug resistance protein 1 (MRP1) inhibitors for cancer chemosensitization. The award period runs from September 5, 2025 through August 31, 2027. The project delivers research and development services aimed at...
- Federal Grant Award Summary The University of Cincinnati received a $383,491 Project Grant from the National Cancer Institute (NCI) under the Cancer Research Manpower program (CFDA 93.398), effective July 1, 2025 through June 30, 2030. This award funds a Training Program in Basic and Translational Oncology designed to develop the next generation of cancer researchers capable of bridging laboratory discoveries with clinical applications. The program addresses a critical gap in the cancer research...
- Federal Project Grant Summary The University of Michigan, Office of Research and Sponsored Projects, received a $319,505 Project Grant from the National Cancer Institute under the Cancer Research Manpower program (CFDA 93.398) awarded August 1, 2025, with completion by July 31, 2030. This five-year award supports the development of comprehensive nationwide training infrastructure in advanced methodological approaches for constructing and optimizing adaptive interventions across the cancer...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded $128,199 to the Regents of the University of Michigan through the Cancer Research Manpower program (CFDA 93.398) effective December 1, 2025, with a completion date of May 31, 2027. This project grant supports biomedical research training and career development in cancer research aligned with the National Cancer Program's strategic priorities. The funded research, titled "Deciphering the Functional Role of PPP2R1A...
- Federal Project Grant Award Summary The National Cancer Institute (NCI) awarded $119,858 to the Regents of the University of Minnesota under the Cancer Biology Research program (CFDA 93.396) on August 7, 2025, for a project extending through July 31, 2030. This project grant supports fundamental research aimed at elucidating and overcoming T cell dysfunction in pancreatic ductal adenocarcinoma (PDA), a disease notoriously resistant to immunotherapy. The research program comprises three...
- Federal Project Grant Award Summary The National Cancer Institute (NCI) awarded the University of Miami's Office of Research Administration within the School of Medicine a Project Grant totaling $109,076.00 under the Cancer Research Manpower program (CFDA 93.398) on December 17, 2025. The award supports biomedical research training and career development initiatives focused on cancer research through September 1, 2029. This project grant funds the institution's capacity to provide integrated...
- Federal Project Grant Award Summary The National Cancer Institute awarded the Regents of the University of Minnesota a $573,262 Project Grant under the Cancer Biology Research program (CFDA 93.396) on April 17, 2026, with completion targeted for March 31, 2031. This award funds the development of autologous humanized leukemia models for immunotherapy testing—specifically, the creation of patient-derived xenograft (PDX) models that incorporate both leukemia cells and immune cells derived from the...
- Federal Project Grant Award Summary The National Cancer Institute awarded a Project Grant of $399,852.00 to the Regents of the University of Minnesota under the Cancer Cause and Prevention Research program (CFDA 93.393) for the period May 1, 2026, through April 30, 2028. This research initiative will develop and validate circulating senescent-associated secretory phenotype (SASP) protein indexes to assess accelerated aging in cancer survivors. The primary deliverable involves creating...
- Federal Grant Award Summary Northern Michigan University received a $462,153 Project Grant award from the National Cancer Institute (NCI) under the Cancer Biology Research program (CFDA 93.396) beginning September 4, 2025, with completion scheduled for August 31, 2026. The project focuses on developing and applying D2HGLO, a novel genetically encoded fluorescent biosensor, to quantify and map intracellular concentrations of D-2-hydroxyglutarate (D-2-HG) in cancer cells. This biosensor...
The National Cancer Institute (NCI) awarded the Regents of the University of Minnesota a $309,761 Project Grant under the Cancer Research Manpower program (CFDA 93.398) effective May 1, 2026, through April 30, 2031. The award funds development and delivery of an innovative training course in biomarker development and applications for cancer prevention research. The course combines virtual didactic modules on chemical carcinogenesis fundamentals with a five-week in-person laboratory training program in state-of-the-art biomarker measurement techniques. The Masonic Cancer Center will deliver structured instruction in biomarker measurement methodologies, data analysis, and interpretation to equip researchers-in-training with practical skills in biomarker-based cancer etiology and prevention studies. The award supports recruitment and training of ten researchers-in-training annually, comprising four U.S.-based participants and six international participants from India, Thailand, and African countries. Beyond technical training, the program delivers instruction in clinical and translational biomarker applications, human subject research ethics, and project management methodologies for designing and implementing cross-sectional and intervention studies. This five-year initiative leverages the University of Minnesota's existing institutional partnerships to build research capacity in cancer prevention across diverse geographic regions with high burden of environmental and lifestyle-related cancer risk factors.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $309.8k | 3/27/26 |