Project Grant R25CA314805
- The National Cancer Institute awarded Cold Spring Harbor Laboratory $199,573 on September 1, 2026, under the Cancer Research Manpower program (CFDA 93.398) to deliver an intensive sixteen-day laboratory and lecture course on metabolomics, held annually each summer from 2026 through 2030. The course combines theoretical instruction and hands-on training in cutting-edge metabolomics approaches to interrogate biochemical state. Metabolomics is a systems-biology technology that simultaneously...
- The National Cancer Institute awarded Cold Spring Harbor Laboratory $704,182 under the Cancer Biology Research program (CFDA 93.396) on June 16, 2026, to dissect non-mutational mechanisms driving benign-to-malignant transition in colorectal cancer. The project uses a novel mouse model that stepwise acquires mutations mirroring human colorectal cancer progression—starting with APC knockout to initiate benign polyps, then inducing KRAS G12V and TP53 loss in rare cells within established polyps...
- The National Cancer Institute awarded Cold Spring Harbor Laboratory $770,911 under the Cancer Biology Research program (CFDA 93.396) on July 1, 2026, to define the role of sphingolipid synthesis in anti-tumor immunity. The project investigates how alterations in lipid metabolism, particularly sphingolipid synthesis catalyzed by serine palmitoyl transferase (SPT), enable cancer cells to evade immune attack in the tumor microenvironment. Preliminary in vivo genetic screens in KRAS-mutant mouse...
- The National Cancer Institute awarded Cold Spring Harbor Laboratory $675,617 on August 1, 2026, under the Cancer Biology Research program (CFDA 93.396) to investigate intercellular metabolic and signaling mechanisms of brain cancer-glia communication driving glioblastoma progression. The project examines how glioblastoma cells reprogram brain microglia—the brain's resident immune cells—to create an immunosuppressive tumor microenvironment that promotes tumor growth. The research focuses on an...
- Federal Grant Award Summary Cold Spring Harbor Laboratory (CSHL) received a $518,342 Project Grant award from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) for the period July 1, 2025 through June 30, 2028. The award supports basic biomedical research investigating communication mechanisms between cancer-associated fibroblasts and neurons in pancreatic cancer progression. This three-year research initiative aligns with the DHA's mission...
- Federal Project Grant Award Summary Cold Spring Harbor Laboratory (CSHL) received a $728,450 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) for the period July 1, 2025 through June 30, 2028. The award supports research investigating communication between cancer-associated fibroblasts and neurons and its role in promoting pancreatic cancer progression. This three-year research project will be conducted at CSHL's...
- The National Cancer Institute awarded the Beckman Research Institute of the City of Hope $162,000 on August 11, 2026, under the Cancer Research Manpower program (CFDA 93.398) to develop and pilot a self-directed e-learning delivery model for clinical cancer genomics education. The recipient will convert selected core recorded didactic modules from its established Intensive Course in Clinical Cancer Genomics into a self-directed e-learning course bundle using theoretically grounded...
- The National Institutes of Health National Cancer Institute awarded Cold Spring Harbor Laboratory $793,679 on August 6, 2026, under the Cancer Biology Research program (CFDA 93.396) to develop whole-body redox maps for metastatic cancer therapy. The project uses protein degradation-based sensing to visualize oxidative stress in vivo across animal models of prostate cancer. The work generates two complementary, immune-competent mouse models—OXIGEM and ROXYCAP—that reveal cellular redox states...
- The federal Project Grant award of $1,224,997.00 was provided by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) to Cold Spring Harbor Laboratory (CSHL) to conduct research aimed at "ENHANCING IMMUNITY IN COLORECTAL CANCER LIVER METASTASES." This grant, with a performance period from August 1, 2024 to July 31, 2028, will allow CSHL, a renowned non-profit research institution, to leverage its expertise in cancer biology, genomics,...
- The Department of Defense's Defense Health Agency has awarded a $1,344,002 Project Grant to Cold Spring Harbor Laboratory (CSHL) under the Military Medical Research and Development program (CFDA 12.420). This four-year grant, running from August 1, 2024 to July 31, 2028, will fund research to enhance immunity in colorectal cancer liver metastases. CSHL, a renowned non-profit research institution, will leverage its expertise in cancer biology, genomics, and molecular biology to advance this...
The National Cancer Institute awarded Cold Spring Harbor Laboratory $105,020 on August 15, 2026, under the Cancer Research Manpower program (CFDA 93.398) to continue a seven-day intensive summer course on pancreatic cancer at the Banbury Center in Cold Spring Harbor, New York. The course serves medical and graduate students, postdoctoral fellows, and established investigators with a comprehensive curriculum covering organ anatomy and physiology, clinical diagnosis and treatment, molecular genetics and pathobiology, advanced research tools including mouse models and genomics platforms, therapeutic development and clinical trials, and institutional resources such as biobanks and funding strategies. The instructional approach combines lead faculty chosen for complementary expertise with distinguished guest lecturers reporting current research findings, supplemented by small group discussion and one-on-one mentoring. The short course duration accommodates both senior and junior participants seeking focused training in a dedicated environment. The award runs through July 31, 2031.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $105.0k | 8/13/26 |