Project Grant R21NS149418
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Leland Stanford Junior University a $423,500 Project Grant (CFDA 93.853: Extramural Research Programs in the Neurosciences and Neurological Disorders) effective June 1, 2026, through May 31, 2028. The award funds research to dissociate neural representations of pain and salience using intracranial human brain recordings. The research will obtain intracranial electroencephalography (iEEG)...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded $745,760 to The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. on August 1, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The project, titled "Astrocyte Calcium Signaling in Chronic Pain," will extend through May 31, 2030. The award supports basic neuroscience research aimed at...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded the University of North Carolina at Chapel Hill a $222,758 Project Grant on August 7, 2025, under the Drug Use and Addiction Research Programs (CFDA 93.279) to support research through July 31, 2027. The award funds a comprehensive neuroscience investigation aimed at delineating how different molecularly defined dorsal root ganglia (DRG) neuron types contribute to pain representation...
- Federal Grant Award Summary Middlebury College received a $540,427 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Drug Use and Addiction Research Programs (CFDA 93.279) awarded August 18, 2025, with completion targeted for June 30, 2028. The project delivers mathematical and computational modeling research aimed at understanding interindividual variation in pain modulation through spinal cord stimulation (SCS). Specifically, the award funds...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke awarded The Johns Hopkins University a $2.71 million Project Grant (effective August 6, 2025 through July 31, 2030) under the Drug Use and Addiction Research Programs (CFDA 93.279) to investigate the neurobiological mechanisms underlying paclitaxel-induced peripheral neuropathy (PIPN). The award supports research utilizing novel whole dorsal root ganglia (DRG) in vivo imaging technology to monitor sensory...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke awarded a $4.04 million Project Grant to the University of Texas at Dallas for a three-year initiative (September 1, 2025 through August 31, 2028) to identify and validate therapeutic targets for chronic pain treatment. The project leverages a CRISPR-based functional genomic screening platform developed by collaborating researchers at the University of Sydney and an extensive human dorsal root ganglion...
- Federal Project Grant Award Summary Dartmouth College received $883,252 in federal funding from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) to support a five-year research initiative (September 1, 2025 – June 30, 2030) titled "Understanding the Role of Anesthesia in Perioperative Organ Injury via Wireless Soft Implants." The project addresses a significant clinical gap in understanding...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded Massachusetts Institute of Technology a Project Grant valued at $591,122 on August 1, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The grant supports a four-year research initiative (through July 31, 2029) to decode and modulate the emotional component of pain through investigation of autonomic nervous system...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Johns Hopkins University a Project Grant totaling $232,938 on February 17, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award supports basic neuroscience research investigating neuronal membrane proteasome-derived (NMP) peptide signaling mechanisms in the peripheral nervous system (PNS), with completion targeted for...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded $407,113 to the University of California, Irvine on August 15, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to support development of novel KV7 channel modulators for pain therapy. This R21 exploratory research grant, which concludes July 31, 2027, will establish an empirical foundation for developing therapies targeting...
Dartmouth-Hitchcock Clinic received a $426,250 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), awarded July 1, 2026, with completion by June 30, 2028. The award supports research investigating translaminar excitatory interneurons in the spinal cord dorsal horn to elucidate neural circuit dynamics underlying the transition from acute to chronic pain. The project employs advanced voltage imaging, electrophysiological, and histological methodologies to analyze a novel genetic marker targeting vertical and antenna cell populations in mice, with the objective of quantifying their involvement in allodynia and nerve injury-induced alterations in inhibitory tone and synaptic balance. Research outcomes from this project are intended to advance understanding of spinal cord neural circuits mediating chronic pain pathophysiology and to inform development of novel non-opioid analgesic therapies that prevent progression from acute to chronic pain following peripheral nerve damage. As a non-profit academic medical center with established capacity in translational neuroscience research, Dartmouth-Hitchcock Clinic will conduct the work at its Lebanon, New Hampshire facility, leveraging institutional partnerships and specialized medical expertise in neurological research aligned with NINDS mission priorities in fundamental neuroscience and neurological disease burden reduction.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $426.3k | 6/30/26 |