Project Grant R21NS145164
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded a Project Grant of $226,530 to The Regents of the University of California, San Francisco under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) effective August 1, 2025, through July 31, 2030. This K23 Career Development Award supports research investigating precision medicine approaches to chronic neuropathic pain through non-invasive...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke awarded a $156,830 Project Grant to The Leland Stanford Junior University (effective August 1, 2025 through July 31, 2026) under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct research on dipeptidase 2 (DPEP2) as a potential non-opioid therapeutic target for surgical pain management. The research aims to elucidate DPEP2's dual role in inflammatory and anti-inflammatory...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded $1,179,715 to The Regents of the University of California, San Francisco under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) on March 15, 2026, for a Project Grant extending through January 31, 2034. The award supports fundamental research investigating pain mechanisms and nociception—the process by which specialized nerve fibers...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Leland Stanford Junior University a Project Grant totaling $125,685 on August 9, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award supports research and development of a bioactive material intervention to address post-stroke dementia, a significant complication affecting approximately 7 million stroke...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded $531,368 to the University of California, San Francisco under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) on August 1, 2025, with a completion date of July 31, 2027. This Project Grant, administered as an administrative supplement to an existing K99 award, funds research investigating the sex-dependent control of nociception...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded $407,113 to the University of California, Irvine on August 15, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to support development of novel KV7 channel modulators for pain therapy. This R21 exploratory research grant, which concludes July 31, 2027, will establish an empirical foundation for developing therapies targeting...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Leland Stanford Junior University a Project Grant totaling $154,274.00 on May 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award supports research and development of small focus, transparent transducers for transcranial ultrasound stimulation (TUS) in mice, with research performance occurring at...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded Massachusetts Institute of Technology a Project Grant valued at $591,122 on August 1, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The grant supports a four-year research initiative (through July 31, 2029) to decode and modulate the emotional component of pain through investigation of autonomic nervous system...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Leland Stanford Junior University a Project Grant of $423,500 on August 1, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. This two-year award, with completion scheduled for July 31, 2027, funds research investigating the mechanisms underlying cognitive dysfunction in neuromyelitis optica (NMO), a central nervous...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Leland Stanford Junior University a project grant of $223,665 under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) effective July 1, 2025, through June 30, 2030. Principal Investigator Dr. Rebecca Levy will conduct research to elucidate how CACNA1C gene variants cause interneuron pathophysiology and cortical network dysfunction. The...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Leland Stanford Junior University a Project Grant totaling $423,500 (awarded June 1, 2026; completion May 31, 2028) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The research project, titled "Dissociating Neural Representations of Pain and Salience Using Intracranial Human Brain Recordings," aims to identify pain-specific neural circuits distinct from salience-processing circuits in the human brain. This distinction is critical for advancing targeted deep brain stimulation therapies for chronic pain treatment, which affects approximately 20% of the population and costs society approximately $600 billion annually. The project deliverables include intracranial electroencephalography (iEEG) measurements and analysis obtained from approximately 20 neurosurgical patients with medically refractory epilepsy as they perform thermal pain and auditory salience tasks. Through this research conducted at Stanford's Palo Alto, California location, investigators will generate empirical evidence identifying neural activity patterns specific to pain sensation versus salience responses, thereby informing future targeted neuromodulation protocols for chronic pain treatment. The research utilizes established institutional review board oversight and adheres to human subjects protections protocols inherent in the NINDS extramural research program framework.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $423.5k | 5/20/26 |