Project Grant R35GM159840
- This Project Grant award from the National Science Foundation's Engineering program (CFDA 47.041) will support research by Trustees of Dartmouth College to develop a novel "Monolithic 3D Neuroelectronics" system. The $364,082 award, with a period of performance from September 1, 2024 to August 31, 2027, will investigate a flexible electronic design and systems research approach to establish a new 3D neural probe paradigm. The goal is to create a powerful tool for neuroscience...
- This Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) to Georgia TECH Research Corp provides $499,896.00 to develop an artificial nervous system for communication between wearable and implantable biomedical devices. The project aims to optimize emitter and receiver networks to enable coordination of sensors and therapeutic actuators throughout the body, with potential applications in areas like sciatic nerve stimulation and controlled drug...
- This National Science Foundation (NSF) Engineering Program (CFDA 47.041) Project Grant award of $600,000 to Dartmouth College aims to develop methodologies for efficiently manufacturing mature human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) to accelerate drug development and cardiac disease modeling. The project will employ biochip design, machine learning, developmental biology, and tissue engineering approaches to enhance the structural and functional maturity of...
- This National Science Foundation (NSF) Engineering (CFDA 47.041) program grant, in the amount of $400,000, supports the development of a tissue-like, converged sensing platform for tracking excitation-contraction dynamics in cardiac organoids. The project aims to: Develop a scalable assembly strategy to fabricate an array of three-dimensional sensor structures using planar semiconducting graphene material, designed to detect both electrical and mechanical stimuli. Evaluate the multifunctional...
- This federal Project Grant award, totaling $457,378.00, was provided by the National Science Foundation's Biological Sciences (CFDA 47.074) Federal Grant Program. The grant supports research by Dartmouth College to investigate how the rodent hippocampus learns from experience and applies that learning to new situations. The research aims to uncover principles of how brains extract generalizable knowledge, by monitoring neural activity in mice during a cognitive learning task. Additionally, the...
- The National Science Foundation (NSF) awarded a three-year, $449,999 Project Grant under their Engineering program (CFDA 47.041) to the University of Cincinnati to develop an implantable biosensor platform that can continuously monitor various biomarkers in the body for over a year. The project aims to create a new class of long-lasting aptamer-based sensors protected by robust porous oxide coatings, which would enable the first practical implantable monitoring system for managing chronic...
- This Project Grant award, funded by the National Science Foundation's Engineering program (CFDA 47.041), supports the development of a novel non-surgical bioelectronic brain implant technology. The $599,918 award to the Massachusetts Institute of Technology (MIT) aims to create intravenously-introduced bioelectronic devices that can autonomously implant in target brain regions without the need for invasive surgery. The proposed technology promises to enable high-resolution brain stimulation...
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $490,841.00 to Trustees of Dartmouth College to conduct research on the mechanical coordination and mechano-biochemical feedback mechanisms underlying epithelial folding during embryogenesis. The research aims to elucidate the regulatory networks and physical principles that govern how tissues generate, sense, and...
- This Project Grant award, totaling $2,252,479.00 and effective from September 1, 2025 to July 31, 2029, was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The award supports fundamental scientific research at Dartmouth College to investigate how protein glycosylation regulates cell fate determination and cell identity. Key objectives include deciphering how glycosylation modulates the functions...
- This Project Grant award of $517,546, awarded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), supports research to optimize, benchmark, and validate a novel multimodal microelectrode array (MEA) probe that integrates fast-scan cyclic voltammetry (FSCV) for sub-second neuromodulator sensing with parallel electrical recording. The research team, led by investigators from Dartmouth College, aims to develop this integrated MEA platform...
This $441,626 federal Project Grant was awarded on September 1, 2025 by the National Institute of General Medical Sciences (CFDA 93.859 Biomedical Research and Research Training program) to the Trustees of Dartmouth College. The grant supports the development of a wireless, soft implant with a protruding microneedle sensor array to continuously and comprehensively track organ physiology and biochemistry. The goal is to elucidate the pathophysiology of perioperative organ injury (POI) and the role of anesthesia in this process. Key deliverables include a 3D-printed, fully biocompatible soft implant that can spatiotemporally probe organs to yield robust interpretations of the pathogenic processes underlying POI. This research aims to improve understanding of how anesthesia impacts POI, which is a major contributor to surgical patient morbidity and mortality, in order to advance diagnostic and treatment approaches.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $441.6k | 8/8/25 |