Project Grant R15AT013512
- This federal Project Grant award, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Drug Use and Addiction Research Programs (CFDA 93.279), is focused on developing novel methods for selectively stimulating nociceptors (pain receptors) and measuring the brain's nociceptive-specific response in both healthy individuals and those with the chronic pain condition fibromyalgia. The $2,314,276 award to Emory University will fund the creation of a new...
- This $453,104 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to explore the role of spinal cord projection neurons in conveying pain signals to the brain. The primary objective is to investigate functional redundancy between two distinct subtypes of spinal projection neurons, those expressing TACR1 (substance P...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $147,486 Project Grant to Carnegie Mellon University under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853). The grant supports research to identify and target neural subpopulations in the spinal cord that mediate chronic pain, with the goal of developing more effective and targeted treatments. The research will analyze cell-type-specific cis-regulatory elements (CREs) in...
- This $2,370,000 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Drug Use and Addiction Research Programs (CFDA 93.279), aims to develop advanced human pluripotent stem cell (HPSC) tools to create comprehensive, region-specific models for studying pain circuitry. The award to Trustees of Tufts College (Tufts University) supports three main objectives: 1) Developing scalable methods to generate region-specific sensory neurons and...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $441,500 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to Duquesne University of the Holy Spirit. The purpose of this 3-year grant, beginning September 2023, is to utilize laboratory data and computational 3-D modeling to analyze the role of the central amygdala in neuropathic pain. Specifically, the project aims to build a proof-of-concept 3-D...
- This $664,772 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research to investigate a novel, non-opioid spinal analgesic mechanism for the treatment of high impact chronic pain. The primary awardee, the University of Texas Southwestern Medical Center, will evaluate the signaling pathway involving the neurotensin receptor 2 (NTSR2) and...
- The federal Project Grant award titled "MODELING INTER-INDIVIDUAL DIFFERENCES TO ADDRESS PAIN OF SICKLE CELL DISEASE (MIDAS)" is funded by the National Institute of Neurological Disorders and Stroke under the Drug Use and Addiction Research Programs (CFDA 93.279). The $1,098,640 award will support a longitudinal study to collect whole-person health data and develop computational models to risk-stratify young adults with sickle cell disease who experience difficult-to-control pain and...
- This $4,649,740.00 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Drug Use and Addiction Research Programs (CFDA 93.279), will fund a study to understand inter-individual differences in the clinical trajectory of chronic musculoskeletal pain (CMSKP). The research aims to develop network representations of patients' lived experience of pain and functional state using language models and home-based videos, and to analyze state transitions in...
- The federal Project Grant award titled "State-Dependent Control of Nociception in Opioid Circuits" is funded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The $667,349 grant aims to investigate the neurobiological mechanisms underlying pain perception and modulation, with a focus on endogenous opioid signaling in the ventrolateral periaqueductal gray...
- This federal Project Grant award of $668,131 was provided by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) to Washington University in Missouri. The award is funding a research project titled "Mesolimbic Adaptations Underlying Altered Reward Sensitivity in Neuropathic Pain" with the goal of understanding the relationship between chronic neuropathic pain and altered dopaminergic function in the brain's reward system. The...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $540,427 to Middlebury College to conduct research on modeling the mechanisms of individual variation in pain modulation by spinal cord stimulation. The 3-year project aims to develop biologically-motivated mathematical models to understand how factors like dorsal column fiber activation and sensory processing in the spinal cord dorsal horn contribute to the variable efficacy of different spinal cord stimulation protocols in alleviating chronic pain in patients. The research will engage undergraduate students at Middlebury College, with mentorship from faculty and graduate students at the University of Michigan. This award strengthens Middlebury's pain research capabilities and provides valuable research opportunities for undergraduate students.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $540.4k | 8/15/25 |