Project Grant R21NS140918
Award Date
12/15/24
Completion Date
11/30/26
Dollars Obligated
$231K
Federal Agency
National Institute of Neurological Disorders and Stroke
Federal Grant Program
93.853
Assistance Type
Project Grant
Place of Performance
Palo Alto, CA 94304, USA
Similar Awards
This $2,249,392 Project Grant was awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Drug Use and Addiction Research Programs (CFDA 93.279) to The Leland Stanford Junior University. The project aims to validate cellular senescence as a target for treating chronic pain in aging populations. Specifically, the research will leverage multiple clinically-relevant mouse models and human post-mortem tissue to characterize the role of senescent neurons and their...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $456,840.00 to The Leland Stanford Junior University to conduct research on the role of pain-facilitating circuits in chronic pain after traumatic brain injury (TBI). The research aims to characterize the functional and electrophysiological changes in descending...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $6,522,833 Project Grant to The Leland Stanford Junior University to conduct a mechanistic randomized clinical trial investigating the central and peripheral nervous system mechanisms of pain relief induced by peripheral nerve stimulation (PNS) for the treatment of refractory chronic neuropathic pain. The 3-year study, funded under the NIH HEAL Initiative's CFDA 93.279 Drug Abuse and Addiction Research Programs, aims...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $2,314,276 to Emory University to develop and test novel methods for delivering and assessing nociceptive-specific (pain-specific) stimuli in both pain-free individuals and those with fibromyalgia. The project aims to overcome limitations in current experimental pain testing by identifying skin regions devoid of innocuous...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $441,500 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to Duquesne University of the Holy Spirit. The purpose of this 3-year grant, beginning September 2023, is to utilize laboratory data and computational 3-D modeling to analyze the role of the central amygdala in neuropathic pain. Specifically, the project aims to build a proof-of-concept 3-D...
This $2,370,000 Project Grant, awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Drug Use and Addiction Research Programs (CFDA 93.279), aims to develop advanced human pluripotent stem cell (HPSC) tools for studying region-specific pain circuits. The key objectives are: 1) Developing scalable methods to generate region-specific sensory neurons and glial subtypes; 2) Creating and characterizing region-specific somatosensory organoids that mimic the in vivo...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, supports research on selective, epineural stimulation of peripheral nerves using interferential electrical fields. The research aims to develop methods for the selective activation of specific nerve fiber populations, which could improve the efficacy and safety of peripheral...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $560,934 to the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University to conduct research on the neural coding and control of pain detection in the somatosensory cortex. The research aims to: 1) define the temporal patterns and characterize the...
This $499,979 federal Project Grant award, provided through the National Institute of Neurological Disorders and Stroke's (NINDS) Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853), supports research by The Salk Institute for Biological Studies to uncover astrocyte contributions to neuropathic pain. The research aims to 1) determine how peripheral nerve injury alters dorsal horn astrocyte function, 2) elucidate how targeted interventions control...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program provides $124,713 to Beth Israel Deaconess Medical Center, Inc. (Bidmc) to conduct research aimed at identifying the neural circuit basis for neuropathic pain in the parabrachial nucleus. The 2-year project (12/1/2024 - 11/30/2026) will leverage advanced imaging techniques and...