This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853), aims to develop and validate methods for selective, epineural electrical stimulation of peripheral nerves. The $638,718 grant will fund research to test the hypothesis that interferential current stimulation (I2CS) delivered through multi-contact cuff electrodes can selectively activate specific nerve fascicles, with the goal of improving the efficacy and safety of peripheral nerve stimulation therapies. The project will establish the efficacy of I2CS compared to other PNS methods, and develop computational models to guide the design and optimization of nerve interface devices. The research will be conducted by the Feinstein Institutes for Medical Research, a non-profit organization that serves as the research arm of Northwell Health.
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