Project Grant R21NS137253

This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, will fund research at the Augusta University Research Institute, Inc. (doing business as Georgia Health Sciences) to investigate the mechanisms linking traumatic brain injury (TBI) to subsequent neurodegeneration and dementia. The $1,975,262 award will support a 3-year study...

This project grant of $224,274, awarded November 27, 2025, through the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), funds fundamental neuroscience research investigating the mechanisms underlying pediatric traumatic brain injury (PTBI) and early life stress (ELS) effects on brain development. The research will employ animal models using lateral fluid percussion...

This $3,109,079 Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) will support research at the University of California, Riverside to investigate the role of traumatic brain injury (TBI) across the lifespan in the development of Alzheimer's disease and related dementias (ADRD). The project will use a closed head injury (CHI) TBI mouse model to examine how ADRD risk factors, such as the APOE4 gene and amyloid-beta, interact with TBI at different life stages...

The National Institutes of Health's National Institute on Aging awarded a $2,366,184 Project Grant to The General Hospital Corporation, doing business as Massachusetts General Hospital, to support research into the mechanisms of circadian and synaptic dysfunction after repetitive mild traumatic brain injury. The three-year award, made on June 1, 2022 under the Aging Research program (CFDA 93.866), will fund work by Drs. Whalen and Lipton to define how interleukin-1 receptor 1-mediated...

The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Johns Hopkins University a $521,963 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, effective August 1, 2025 through June 30, 2030. This award funds a research investigation into gut serotonergic signaling in traumatic brain injury (TBI), addressing a significant public health concern with an estimated annual economic burden of $56.3 billion....

This Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) will support research to study how astrocytes, a critical cell type in the brain, respond to mechanical forces and strain associated with traumatic brain injury (TBI). The $705,806 award to Tufts University will fund the development of controlled 3D brain-like cell culture environments and ex vivo brain cultures to quantify astrocytes' acute and chronic responses to mechanical perturbation...

Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded a Project Grant totaling $453,970 to the Hugo W. Moser Research Institute at Kennedy Krieger, Inc. under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The award, effective June 1, 2025 through May 31, 2027, funds research investigating the therapeutic effects of intranasal heparin-binding epidermal growth factor (HB-EGF)...

Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded $453,860 to Henry Ford Health + Michigan State University Health Sciences on June 1, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. This project grant funds preclinical research investigating the metabolic regulation of neutrophil extracellular traps (NETs) in traumatic brain injury (TBI). The research will examine...

Federal Project Grant Award Summary The University of Pittsburgh received a $571,404 Project Grant awarded May 30, 2025, by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853). The research project, titled "Adipokines as Novel Therapy to Promote Functional Recovery After Experimental Traumatic Brain Injury," will extend through April 30, 2030. This award funds...

This Project Grant award, funded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, aims to investigate the potential impact of a low-fat, high-fiber diet in limiting traumatic brain injury (TBI)-induced neurodegenerative and inflammatory changes in a mouse model. The $498,713.00 award, with a performance period from July 2024 to June 2027, will support research to...